Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 3/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9333909 | 0.84 | HSD17B10 (0.63) | HSD17B10HPGDALDH1A1KDM4EALOX15 | |
| SCHEMBL16674880 | 0.84 | HSD17B10 (0.63) | HSD17B10HPGDALDH1A1KDM4EALOX15 | |
| SCHEMBL9650824 | 0.84 | HSD17B10 (0.55) | HSD17B10HPGDALDH1A1KDM4EALOX15 | |
| SCHEMBL27890099 | 0.83 | HSD17B10 (0.61) | HSD17B10HPGDALDH1A1KDM4EALOX15 | |
| SCHEMBL15529211 | 0.82 | HPGD (0.69) | HSD17B10HPGDALDH1A1KDM4EALOX15 | |
| Bicarbonate SCHEMBL27678150 | 0.81 | HSD17B10 (0.59) | HSD17B10HPGDALDH1A1KDM4EALOX15 | |
| SCHEMBL11847525 | 0.80 | MAPT (0.58) | HSD17B10AKR1B1ALOX15CXCL8KMT2A | |
| SCHEMBL31112176 | 0.80 | MAPT (0.58) | HSD17B10AKR1B1ALOX15CXCL8KMT2A | |
| SCHEMBL3635482 | 0.79 | HPGD (0.76) | HSD17B10HPGDALDH1A1KDM4EALOX15 | |
| SCHEMBL2052137 | 0.79 | KDM4E (0.56) | HSD17B10HPGDALDH1A1KDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051549-A1 | TREATMENT OF FABRICS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 2000-11-15 | — | — | EP | claimed |
| WO-1999039039-A1 | TREATMENT OF FABRICS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1999-08-05 | — | — | WO | claimed |