SCHEMBL15529503

SCHEMBL15529503

CCCC[Sn](c1cc(C)ccc1C)(c1cc(C)ccc1C)c1cc(C)ccc1C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.34
TDP1 Q9NUW8 2/20 0.34
TLR8 Q9NR97 4/20 0.33
TAAR1 Q96RJ0 1/20 0.33
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
LMNA P02545 1/20 0.33
ALOX12 P18054 1/20 0.33
KDM4E B2RXH2 1/20 0.32
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32
TP53 P04637 2/20 0.31
NPC1 O15118 1/20 0.31
GPX4 P36969 1/20 0.31
RAB9A P51151 1/20 0.31
PAX8 Q06710 1/20 0.31
TSHR P16473 1/20 0.31
SKP2 Q13309 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15529423 0.94 TLR8 (0.36) ALDH1A1TDP1TLR8TAAR1CNR1
SCHEMBL15530222 0.93 CNR2 (0.38) ALDH1A1TDP1TLR8TAAR1CNR1
SCHEMBL15529680 0.93 CNR2 (0.38) ALDH1A1TDP1TLR8TAAR1CNR1
SCHEMBL15529494 0.93 CNR2 (0.38) ALDH1A1TDP1TLR8TAAR1CNR1
SCHEMBL15529787 0.88 TDP1 (0.37) ALDH1A1TDP1TAAR1LMNAKDM4E
SCHEMBL1453413 0.85 TLR8 (0.36) ALDH1A1TDP1TLR8TAAR1CNR1
SCHEMBL15529745 0.79 TDP1 (0.39) ALDH1A1TDP1TAAR1LMNAKDM4E
SCHEMBL15529220 0.76 ALDH1A1 (0.33) ALDH1A1TDP1TAAR1
SCHEMBL5951974 0.73 MAPT (0.38) ALDH1A1TDP1TLR8CNR1CNR2
SCHEMBL15530127 0.71 ALDH1A1 (0.35) ALDH1A1TDP1TAAR1LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013167585-A2 RECYCLING OF ORGANOTIN COMPOUNDS UNIVERSITEIT ANTWERPEN (BE) 2013-11-14 WO disclosed