Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.60 |
| ▸ | FAAH | O00519 | 4/20 | 0.57 |
| ▸ | HTR2C | P28335 | 3/20 | 0.57 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1960679 | 0.95 | TRPV1 (0.58) | TRPV1FAAHHTR2CGRIN2BNPC1 | |
| Hydrochloric Acid SCHEMBL2197351 | 0.94 | TRPV1 (0.57) | TRPV1FAAHHTR2CGRIN2BNPC1 | |
| SCHEMBL3768246 | 0.88 | TRPV1 (0.60) | TRPV1FAAHHTR2CGRIN2BNPC1 | |
| SCHEMBL30791537 | 0.86 | POLB (0.66) | TRPV1FAAHHTR2CGRIN2BNPC1 | |
| SCHEMBL1758868 | 0.86 | POLB (0.66) | TRPV1FAAHHTR2CGRIN2BNPC1 | |
| SCHEMBL6304805 | 0.85 | HTR2C (0.70) | TRPV1FAAHHTR2CGRIN2BNPC1 | |
| Hydrochloric Acid SCHEMBL2194067 | 0.85 | POLB (0.68) | TRPV1FAAHHTR2CGRIN2BNPC1 | |
| SCHEMBL32668648 | 0.85 | GRIN2B (0.55) | TRPV1FAAHHTR2CGRIN2BLMNA | |
| SCHEMBL16707623 | 0.84 | LMNA (0.67) | TRPV1FAAHHTR2CLMNAHTR2A | |
| SCHEMBL12509405 | 0.83 | CYP3A4 (0.63) | TRPV1FAAHGRIN2BNPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2852585-A1 | NAMPT INHIBITORS | AbbVie Inc. (US) | 2015-04-01 | — | — | EP | disclosed |
| WO-2013170113-A1 | NAMPT INHIBITORS | ABBVIE INC. (US) | 2013-11-14 | — | — | WO | disclosed |