SCHEMBL15529682

SCHEMBL15529682

CCCCCC[Sn](c1c(C)cc(C)cc1C)(c1c(C)cc(C)cc1C)c1c(C)cc(C)cc1C

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 3/20 0.34
HTT P42858 2/20 0.34
CNR2 P34972 2/20 0.33
SIRT2 Q8IXJ6 1/20 0.33
TSHR P16473 1/20 0.32
THRB P10828 1/20 0.32
HPGD P15428 2/20 0.32
POLB P06746 1/20 0.32
CYP3A4 P08684 1/20 0.31
CNR1 P21554 1/20 0.31
NOS2 P35228 1/20 0.31
NPC1 O15118 1/20 0.31
MAPK1 P28482 1/20 0.31
RAB9A P51151 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
ESR1 P03372 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15530045 0.92 HPGD (0.33) HTTSIRT2TSHRHPGDPOLB
SCHEMBL2481986 0.75 HPGD (0.33) HTTSIRT2TSHRHPGDPOLB
Heptane SCHEMBL1614601 0.72 TSHR (0.53) PTGS2HTTCNR2TSHRTHRB
Decane SCHEMBL8857602 0.72 TSHR (0.53) PTGS2HTTCNR2TSHRTHRB
Dodecane SCHEMBL2452907 0.72 TSHR (0.53) PTGS2HTTCNR2TSHRTHRB
Hexadecane SCHEMBL2456024 0.72 TSHR (0.53) PTGS2HTTCNR2TSHRTHRB
SCHEMBL15529680 0.72 CNR2 (0.38) HTTCNR2HPGDCNR1NPC1
SCHEMBL15529494 0.72 CNR2 (0.38) HTTCNR2HPGDCNR1NPC1
SCHEMBL2456019 0.70 PTGS2 (0.48) PTGS2HTTHPGDCYP3A4NPC1
SCHEMBL1988145 0.70 PTGS2 (0.48) PTGS2HTTHPGDCYP3A4NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013167585-A2 RECYCLING OF ORGANOTIN COMPOUNDS UNIVERSITEIT ANTWERPEN (BE) 2013-11-14 WO disclosed