Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 15/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL164533 | 0.86 | NAMPT (1.00) | NAMPT | |
| SCHEMBL15530331 | 0.86 | NAMPT (0.56) | NAMPT | |
| SCHEMBL15530680 | 0.85 | NAMPT (0.55) | NAMPT | |
| SCHEMBL15530643 | 0.85 | NAMPT (0.60) | NAMPTKDM4E | |
| SCHEMBL15530430 | 0.85 | NAMPT (0.61) | NAMPT | |
| SCHEMBL15531122 | 0.81 | NAMPT (0.53) | NAMPT | |
| SCHEMBL27920150 | 0.81 | NAMPT (0.76) | NAMPTSMN1; SMN2 | |
| SCHEMBL15530845 | 0.79 | NAMPT (0.66) | NAMPTMEN1KMT2A | |
| SCHEMBL15530163 | 0.77 | NAMPT (0.58) | NAMPTMEN1KMT2A | |
| SCHEMBL15530043 | 0.75 | NAMPT (0.72) | NAMPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013170191-A1 | METHODS OF USING ANTAGONISTS OF NAD BIOSYNTHESIS FROM NICOTINAMIDE | GENENTECH, INC. (US) | 2013-11-14 | — | — | WO | disclosed |