SCHEMBL155309

SCHEMBL155309

C=C(C)C(=O)OCCC(F)(F)C(F)(F)C(F)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.43
TSHR P16473 3/20 0.42
ALDH1A1 P00352 2/20 0.38
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
HTT P42858 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31757149 0.98 THRB (0.42) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL13024793 0.95 THRB (0.42) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL17603217 0.94 THRB (0.39) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL711905 0.94 THRB (0.41) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL711199 0.94 THRB (0.41) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL712016 0.94 THRB (0.41) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL27797693 0.92 THRB (0.40) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL27776673 0.91 THRB (0.39) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL27776676 0.91 THRB (0.39) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL1536985 0.90 THRB (0.46) THRBTSHRALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 320 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3247328-B1 METHODS, COMPOSITIONS, AND SYSTEMS FOR DELIVERING THERAPEUTIC AND DIAGNOSTIC AGENTS INTO CELLS GENEVANT SCIENCES GMBH (CH) 2026-01-07 EP claimed
US-20230038687-A1 METHODS, COMPOSITIONS, AND SYSTEMS FOR DELIVERING THERAPEUTIC AND DIAGNOSTIC AGENTS INTO CELLS GENEVANT SCIENCES GMBH (CH) 2023-02-09 US claimed
US-20220031847-A1 THERAPEUTIC METHODS GENEVANT SCIENCES GMBH (CH) 2022-02-03 US claimed
EP-3873530-A1 THERAPEUTIC METHODS Genevant Sciences GmbH (CH) 2021-09-08 EP claimed
US-20200398289-A1 ARTICLES FOR MANIPULATING IMPINGING LIQUIDS AND ASSOCIATED METHODS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2020-12-24 US claimed
US-20190118232-A1 ARTICLES FOR MANIPULATING IMPINGING LIQUIDS AND ASSOCIATED METHODS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2019-04-25 US claimed
EP-3247328-A1 METHODS, COMPOSITIONS, AND SYSTEMS FOR DELIVERING THERAPEUTIC AND DIAGNOSTIC AGENTS INTO CELLS PhaseRx, Inc. (US) 2017-11-29 EP claimed
US-9498934-B2 Grafted polymer surfaces for dropwise condensation, and associated methods of use and manufacture MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2016-11-22 US claimed
US-20160333187-A1 SYSTEMS AND METHODS FOR CONTROLLING THE DEGRADATION OF DEGRADABLE MATERIALS DropWise Technologies Corp. 2016-11-17 US claimed
US-20160296985-A1 ARTICLES FOR MANIPULATING IMPINGING LIQUIDS AND ASSOCIATED METHODS MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2016-10-13 US claimed
WO-2016118697-A9 METHODS, COMPOSITIONS, AND SYSTEMS FOR DELIVERING THERAPEUTIC AND DIAGNOSTIC AGENTS INTO CELLS PHASERX, INC. (US) 2016-09-29 WO claimed
WO-2016118697-A1 METHODS, COMPOSITIONS, AND SYSTEMS FOR DELIVERING THERAPEUTIC AND DIAGNOSTIC AGENTS INTO CELLS PHASERX, INC. (US) 2016-07-28 WO claimed
US-20160159038-A1 GRAFTED POLYMER SURFACES FOR DROPWISE CONDENSATION, AND ASSOCIATED METHODS OF USE AND MANUFACTURE MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2016-06-09 US claimed
EP-2956248-A1 GRAFTED POLYMER SURFACES FOR DROPWISE CONDENSATION, AND ASSOCIATED METHODS OF USE AND MANUFACTURE Massachusetts Institute of Technology (US) 2015-12-23 EP claimed
CN-105121036-A Grafted polymer surfaces for dropwise condensation, and associated methods of use and manufacture MASSACHUSETTS INST TECHNOLOGY 2015-12-02 CN claimed
US-20140314982-A1 GRAFTED POLYMER SURFACES FOR DROPWISE CONDENSATION, AND ASSOCIATED METHODS OF USE AND MANUFACTURE MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2014-10-23 US claimed
WO-2014127304-A1 GRAFTED POLYMER SURFACES FOR DROPWISE CONDENSATION, AND ASSOCIATED METHODS OF USE AND MANUFACTURE MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2014-08-21 WO claimed
US-20100055463-A1 HYDROPHOBIC CARBON BLACK INTERMEDIATE TRANSFER COMPONENTS XEROX CORPORATION (US) 2010-03-04 US claimed
US-7031589-B2 Material for attenuating light signals with low reflectance in a fiber optic network FURUKAWA ELECTRIC NORTH AMERICA (US) 2006-04-18 US claimed
US-20040264908-A1 Material for attenuating light signals with low reflectance in a fiber optic network FURUKAWA ELECTRIC NORTH AMERICA, INC. 2004-12-30 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230038687-A1 METHODS, COMPOSITIONS, AND SYSTEMS FOR DELIVERING THERAPEUTIC AND DIAGNOSTIC AGENTS INTO CELLS CD63, LIPA, NPC1L1 THRB 4401/4885TSHR 3638/4885ALDH1A1 3899/4885
US-20220031847-A1 THERAPEUTIC METHODS NUP205, HNRNPH3, FUS THRB 3746/4885TSHR 1938/4885ALDH1A1 4243/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.