Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.59 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.59 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | PDE4A | P27815 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15933915 | 1.00 | LIMK1 (0.70) | LIMK1TSHRLMNACSNK2A2CSNK2B | |
| SCHEMBL15923688 | 0.83 | LIMK1 (0.50) | LIMK1TSHRLMNACSNK2A2CSNK2B | |
| SCHEMBL15923690 | 0.83 | LIMK1 (0.50) | LIMK1TSHRLMNACSNK2A2CSNK2B | |
| SCHEMBL15933927 | 0.83 | LIMK1 (0.50) | LIMK1TSHRLMNACSNK2A2CSNK2B | |
| SCHEMBL14459722 | 0.82 | LIMK1 (0.70) | LIMK1TSHRLMNACSNK2A2CSNK2B | |
| SCHEMBL17850662 | 0.82 | LIMK1 (0.70) | LIMK1TSHRLMNACSNK2A2CSNK2B | |
| SCHEMBL15534294 | 0.81 | LIMK1 (0.60) | LIMK1TSHRLMNACSNK2A2CSNK2B | |
| SCHEMBL18135597 | 0.80 | LIMK1 (0.61) | LIMK1LMNACSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL16384778 | 0.77 | LIMK1 (0.78) | LIMK1LMNACSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL923855 | 0.76 | LIMK1 (0.66) | LIMK1TSHRLMNACSNK2A2CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2852595-B1 | SUBSTITUTED BENZOTHIENOPYRIMIDINES | Bayer Pharma AG (DE) | 2016-06-22 | — | — | EP | disclosed |
| US-20160159816-A1 | SUBSTITUTED THIENOPYRIMIDINES AND PHARMACEUTICAL USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-06-09 | — | — | US | disclosed |
| US-9296757-B2 | Substituted benzothienopyrimidines | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-03-29 | — | — | US | disclosed |
| US-20150152121-A1 | Substituted Benzothienopyrimidines | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-06-04 | — | — | US | disclosed |
| EP-2852595-A1 | SUBSTITUTED BENZOTHIENOPYRIMIDINES | Bayer Pharma Aktiengesellschaft (DE) | 2015-04-01 | — | — | EP | disclosed |
| WO-2013174735-A1 | SUBSTITUTED BENZOTHIENOPYRIMIDINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2013-11-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150152121-A1 | Substituted Benzothienopyrimidines | CCNA1, CCNT2, TYMP | LIMK1 4038/4885TSHR 2655/4885LMNA 1889/4885 |
| US-20160159816-A1 | SUBSTITUTED THIENOPYRIMIDINES AND PHARMACEUTICAL USE THEREOF | TYMP, DPYD, TYMS | LIMK1 3605/4885TSHR 3295/4885LMNA 4202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.