Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.56 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.56 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.56 |
| ▸ | CDK2 | P24941 | 1/20 | 0.56 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | PDE4A | P27815 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14459722 | 1.00 | LIMK1 (0.70) | LIMK1TSHRLMNACSNK2A2CSNK2B | |
| SCHEMBL13641045 | 0.90 | MEN1 (0.60) | LIMK1TSHRLMNACSNK2A2CSNK2B | |
| SCHEMBL10343475 | 0.90 | MEN1 (0.60) | LIMK1TSHRLMNACSNK2A2CSNK2B | |
| SCHEMBL19523758 | 0.83 | HTT (0.63) | LIMK1TSHRLMNACSNK2A2CSNK2B | |
| SCHEMBL17797480 | 0.83 | LIMK1 (0.50) | LIMK1TSHRLMNACSNK2A2CSNK2B | |
| SCHEMBL17816394 | 0.83 | LIMK1 (0.50) | LIMK1TSHRLMNACSNK2A2CSNK2B | |
| SCHEMBL10343608 | 0.83 | HTT (0.63) | LIMK1TSHRLMNACSNK2A2CSNK2B | |
| SCHEMBL15933915 | 0.82 | LIMK1 (0.70) | LIMK1TSHRLMNACSNK2A2CSNK2B | |
| SCHEMBL15533548 | 0.82 | LIMK1 (0.70) | LIMK1TSHRLMNACSNK2A2CSNK2B | |
| SCHEMBL17294588 | 0.81 | LIMK1 (0.47) | LIMK1TSHRLMNACSNK2A2CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2852595-B1 | SUBSTITUTED BENZOTHIENOPYRIMIDINES | Bayer Pharma AG (DE) | 2016-06-22 | — | — | EP | disclosed |