Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.56 |
| ▸ | SMO | Q99835 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | PRNP | P04156 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4301854 | 0.82 | MAP4K4 (0.56) | SMO | |
| SCHEMBL20505074 | 0.79 | NPC1 (0.41) | KMT2AMEN1ALDH1A1SMOGAA | |
| SCHEMBL13588460 | 0.79 | KMT2A (0.65) | KDM4EKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL1742541 | 0.78 | SMN1; SMN2 (0.56) | KDM4EKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL4407327 | 0.77 | SMN1; SMN2 (0.55) | KDM4EKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL11781911 | 0.76 | KMT2A (0.58) | KDM4EKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL3963492 | 0.76 | KDM4E (0.47) | KDM4EMAPTALDH1A1HPGDTDP1 | |
| SCHEMBL4103913 | 0.75 | CYP1A2 (0.52) | KDM4EKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL23973240 | 0.75 | KMT2A (0.63) | KDM4EKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL30167511 | 0.75 | KMT2A (0.63) | KDM4EKMT2AMEN1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013175415-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AND USES THEREOF | Piramal Enterprises Limited (IN) | 2013-11-28 | — | — | WO | disclosed |