Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.85 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.85 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.85 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.85 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.85 |
| ▸ | MEN1 | O00255 | 1/20 | 0.85 |
| ▸ | TP53 | P04637 | 1/20 | 0.85 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.85 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.77 |
| ▸ | CNR1 | P21554 | 1/20 | 0.68 |
| ▸ | TERT | O14746 | 3/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.61 |
| ▸ | PPARG | P37231 | 3/20 | 0.61 |
| ▸ | PPARD | Q03181 | 3/20 | 0.61 |
| ▸ | PPARA | Q07869 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | BLM | P54132 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | FABP4 | P15090 | 2/20 | 0.61 |
| ▸ | GMNN | O75496 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oleamide SCHEMBL15533927 | 1.00 | FAAH (0.85) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| Oleamide SCHEMBL6366127 | 0.96 | FAAH (0.85) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| Oleamide SCHEMBL6366123 | 0.96 | FAAH (0.85) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| SCHEMBL9418870 | 0.93 | FAAH (0.79) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| SCHEMBL9418871 | 0.93 | FAAH (0.79) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| Oleamide SCHEMBL2906344 | 0.93 | FAAH (0.85) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| SCHEMBL24340776 | 0.92 | FAAH (1.00) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| SCHEMBL21501560 | 0.92 | FAAH (1.00) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| SCHEMBL284607 | 0.92 | FAAH (1.00) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| SCHEMBL21983255 | 0.92 | FAAH (1.00) | FAAHSOAT1CYP1A2CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10072230-B2 | Method for reducing engine wear with lubricants comprising 2-hydroxyalkylamide friction modifying/anti-wear compositions | CHEMTURA CORP (US) | 2018-09-11 | — | — | US | disclosed |
| US-9562207-B2 | Lubricants comprising 2-hydroxyalkylamide friction modifying compositions | CHEMTURA CORPORATION (US) | 2017-02-07 | — | — | US | disclosed |
| US-20160251591-A1 | METHOD FOR REDUCING ENGINE WEAR WITH LUBRICANTS COMPRISING 2-HYDROXYALKYLAMIDE FRICTION MODIFYING / ANTI-WEAR COMPOSITIONS | CHEMTURA CORP (US) | 2016-09-01 | — | — | US | disclosed |
| US-20150376537-A1 | Lubricants Comprising 2-Hydroxyalkylamide Friction Modifying Compositions | CHEMTURA CORPORATION (US) | 2015-12-31 | — | — | US | disclosed |
| EP-2852658-A1 | LUBRICANTS COMPRISING 2-HYDROXYALKYLAMIDE FRICTION MODIFYING COMPOSITIONS | Chemtura Corporation (US) | 2015-04-01 | — | — | EP | disclosed |
| WO-2013176802-A1 | LUBRICANTS COMPRISING 2-HYDROXYALKYLAMIDE FRICTION MODIFYING COMPOSITIONS | CHEMTURA CORPORATION (US) | 2013-11-28 | — | — | WO | disclosed |