Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15533958 | 1.00 | FASN (0.31) | FASN | |
| SCHEMBL736814 | 0.74 | FASN (0.43) | FASN | |
| Hydrochloric Acid SCHEMBL4538069 | 0.73 | FASN (0.42) | FASN | |
| SCHEMBL15536059 | 0.72 | FASN (0.37) | FASN | |
| SCHEMBL15536061 | 0.72 | FASN (0.37) | FASN | |
| SCHEMBL15543989 | 0.70 | FASN (0.31) | FASN | |
| SCHEMBL736458 | 0.69 | FASN (0.39) | FASN | |
| SCHEMBL738551 | 0.69 | FASN (0.39) | FASN | |
| SCHEMBL15546808 | 0.69 | ALDH1A1 (0.33) | — | |
| SCHEMBL735829 | 0.68 | FASN (0.39) | FASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014008223-A2 | FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2014-01-09 | — | — | WO | disclosed |
| WO-2013177253-A2 | FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2013-11-28 | — | — | WO | disclosed |