Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 5/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CKS1B | P61024 | 1/20 | 0.46 |
| ▸ | SKP1 | P63208 | 1/20 | 0.46 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.46 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15535416 | 0.86 | MAPT (0.51) | ALKMAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL15534485 | 0.85 | KMT2A (0.48) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL22738197 | 0.85 | SMN1; SMN2 (0.48) | ALKMAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL15666121 | 0.85 | CKS1B (0.48) | ALKMAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL15533552 | 0.85 | GPR119 (0.54) | ALKMAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL15533996 | 0.83 | EGLN2 (0.55) | ALKMAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL15534257 | 0.82 | MAPT (0.52) | ALKMAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL2420167 | 0.81 | POLB (0.52) | MAPTLMNASMN1; SMN2ALDH1A1PDK2 | |
| SCHEMBL15534051 | 0.81 | MAOB (0.47) | MAPTLMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL3069067 | 0.80 | GPR119 (0.53) | ABCB1MAPTLMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013177253-A2 | FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2013-11-28 | — | — | WO | disclosed |