Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 5/20 | 0.56 |
| ▸ | HTR3A | P46098 | 2/20 | 0.56 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.50 |
| ▸ | RBP4 | P02753 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3855621 | 0.99 | CHRNA7 (0.55) | CHRNA7HTR3AEIF4A3RBP4RAB9A | |
| SCHEMBL1572778 | 0.92 | CHRNA7 (0.52) | CHRNA7HTR3AEIF4A3RBP4RAB9A | |
| SCHEMBL17347549 | 0.92 | KDM4E (0.50) | CHRNA7HTR3AEIF4A3RBP4RAB9A | |
| Hydrochloric Acid SCHEMBL4223898 | 0.91 | CHRNA7 (0.51) | CHRNA7HTR3AEIF4A3RBP4RAB9A | |
| SCHEMBL17347527 | 0.88 | CHRNA7 (0.51) | CHRNA7HTR3AEIF4A3RBP4RAB9A | |
| SCHEMBL3856372 | 0.85 | RBP4 (0.49) | CHRNA7HTR3AEIF4A3RBP4MAPT | |
| SCHEMBL3864878 | 0.85 | MAPT (0.42) | CHRNA7HTR3AEIF4A3RBP4RAB9A | |
| SCHEMBL3856255 | 0.85 | RBP4 (0.49) | CHRNA7HTR3AEIF4A3RBP4MAPT | |
| SCHEMBL3856947 | 0.85 | RBP4 (0.50) | CHRNA7HTR3ARBP4 | |
| Bromide SCHEMBL3859271 | 0.84 | RBP4 (0.49) | CHRNA7HTR3ARBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7589201-B2 | Derivatives of 1,4-diazabicyclo[3.2.1]octanecarboxamide, preparation method thereof and use of same in therapeutics | SANOFI-AVENTIS (FR) | 2009-09-15 | — | — | US | claimed |
| US-20070155749-A1 | DERIVATIVES OF 1,4-DIAZABICYCLO[3.2.1]OCTANECARBOXAMIDE, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2007-07-05 | — | — | US | claimed |
| EP-1709052-B1 | DERIVATIVES OF 1,4-DIAZABICYCLO 3.2.1OCTANECARBOXAMIDE, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS | SANOFI AVENTIS (FR) | 2011-04-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155749-A1 | DERIVATIVES OF 1,4-DIAZABICYCLO[3.2.1]OCTANECARBOXAMIDE, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS | CNR1, CNR2, NPY1R | CHRNA7 1666/4885HTR3A 2836/4885EIF4A3 2153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.