SCHEMBL155352

SCHEMBL155352

COc1ccc(S(=O)(=O)O)cc1[NH]

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.48
TSHR P16473 1/20 0.48
MAPK1 P28482 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.44
CASR P41180 1/20 0.43
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
MMP1 P03956 1/20 0.42
MMP2 P08253 1/20 0.42
MMP9 P14780 1/20 0.42
MMP8 P22894 1/20 0.42
MMP13 P45452 1/20 0.42
GPBAR1 Q8TDU6 1/20 0.41
F2 P00734 2/20 0.41
PRSS1 P07477 2/20 0.41
PRSS2 P07478 2/20 0.41
PRSS3 P35030 2/20 0.41
LMNA P02545 2/20 0.40
HTT P42858 1/20 0.40
PTGS1 P23219 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL156031 0.85 TSHR (0.48) POLBTSHRMAPK1SMN1; SMN2CASR
SCHEMBL29362862 0.82 MAPK1 (0.70) POLBTSHRMAPK1SMN1; SMN2GPBAR1
SCHEMBL3493614 0.82 MAPK1 (0.70) POLBTSHRMAPK1SMN1; SMN2GPBAR1
SCHEMBL1806000 0.81 PTGS2 (0.53) POLBTSHRMAPK1CA1CA2
SCHEMBL10497763 0.81 MAPK1 (0.68) POLBTSHRMAPK1SMN1; SMN2GPBAR1
Ammonia Solution, Strong SCHEMBL9646716 0.81 MAPK1 (0.68) POLBTSHRMAPK1SMN1; SMN2GPBAR1
Hydrochloric Acid SCHEMBL27568289 0.81 MAPK1 (0.68) POLBTSHRMAPK1SMN1; SMN2GPBAR1
SCHEMBL2123784 0.81 PTGS1 (0.57) POLBTSHRMAPK1SMN1; SMN2CA1
SCHEMBL27996488 0.81 MAPK1 (0.68) POLBTSHRMAPK1SMN1; SMN2GPBAR1
SCHEMBL9638989 0.81 S1PR3 (0.46) TSHRMAPK1SMN1; SMN2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0333656-A1 Reactive dyes, process for their preparation and their use CIBA-GEIGY AG (CH) 1989-09-20 EP claimed
US-8668321-B2 Ink jet recording method and ink jet recording apparatus CANON KABUSHIKI KAISHA (JP) 2014-03-11 US disclosed
EP-1988135-B1 Ink, ink jet recording method, ink cartridge, recording unit, and ink jet recording apparatus CANON KK (JP) 2013-04-03 EP disclosed
US-8404036-B2 Water-soluble near-infrared absorbing coloring matters and aqueous inks containing same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2013-03-26 US disclosed
US-8328346-B2 Ink jet recording method and ink jet recording apparatus CANON KABUSHIKI KAISHA (JP) 2012-12-11 US disclosed
US-20120056931-A1 MAGENTA COLORING MATTER, INK COMPOSITION, AND COLORED BODY NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2012-03-08 US disclosed
US-20110310202-A1 INK JET RECORDING METHOD AND INK JET RECORDING APPARATUS CANON KABUSHIKI KAISHA (JP) 2011-12-22 US disclosed
US-20110310164-A1 INK JET RECORDING METHOD AND INK JET RECORDING APPARATUS CANON KABUSHIKI KAISHA (JP) 2011-12-22 US disclosed
EP-2017309-B1 PORPHYRAZINE DYE, INK, INK SET, AND COLORED MATTER NIPPON KAYAKU KK (JP) 2011-10-05 EP disclosed
EP-1985668-B1 NOVEL PORPHYRAZINE DYE, INK, INK SET, AND COLORED MATERIAL NIPPON KAYAKU KK (JP) 2011-09-21 EP disclosed
US-4325705-A Anthraquinone reactive dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1982-04-20 US disclosed
EP-0047863-A2 Reactive phthalocyanine hyes, process for their preparation and their use in dyeing materials containing hydroxyle groups and/or nitrogen BAYER AG (DE) 1982-03-24 EP disclosed
US-4300902-A Coloration process IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1981-11-17 US disclosed
EP-0012342-A1 Anthraquinone reactive dyestuffs and their use in dyeing and printing materials that contain hydroxyl groups or amide groups BAYER AG (DE) 1980-06-25 EP disclosed
EP-0012341-A1 Anthraquinone reactive dyestuffs and their use in dyeing materials that contain hydroxyl or amide groups BAYER AG (DE) 1980-06-25 EP disclosed
US-4191687-A Reactive dyestuffs containing the residue of 1-hydroxy-7-amino-8-(5'-amino-2',4'-disulphophenylazo)naphthalene-3,6-disulphonic acid IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1980-03-04 US disclosed
US-4169705-A Coloration process IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-10-02 US disclosed
US-4153413-A DYEING POLYESTER OR CELLULOSE TRIACETATE WITH A DISPERSE AZO DYESTUFF, HEAT TREATMENT, PADDING, PRINTING IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-05-08 US disclosed
US-4147510-A Coloration process IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-04-03 US disclosed
US-4134723-A DYEING AROMATIC POLYESTER/POLYAMIDE OR AROMATIC POLYESTER/CELLULOSE BLENDS WITH DISPERSE MONOAZO DYE, ALKALINE BATH IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-01-16 US disclosed