Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | SCN1A | P35498 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15535748 | 0.86 | — | — | |
| SCHEMBL20656504 | 0.86 | ALDH1A1 (0.35) | HTTMAPK1ALDH1A1CYP1A2CHRM2 | |
| SCHEMBL20656538 | 0.80 | EBP (0.35) | SIGMAR1 | |
| SCHEMBL30422120 | 0.76 | HTT (0.37) | HTTMAPK1ALDH1A1CYP1A2CHRM2 | |
| SCHEMBL612716 | 0.75 | SMN1; SMN2 (0.46) | HTTMAPK1ALDH1A1CYP1A2CHRM2 | |
| SCHEMBL15536318 | 0.74 | USP2 (0.45) | HTTMAPK1ALDH1A1USP2KDM4E | |
| SCHEMBL28862350 | 0.73 | ALDH1A1 (0.44) | HTTMAPK1ALDH1A1CYP1A2CHRM2 | |
| SCHEMBL20656501 | 0.73 | HRH3 (0.33) | ALDH1A1SCN1ASCN2ASCN3AHRH3 | |
| SCHEMBL20656539 | 0.73 | — | — | |
| SCHEMBL9516216 | 0.72 | ALDH1A1 (0.43) | HTTMAPK1ALDH1A1CYP1A2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2852625-B1 | SILANE GROUPS CONTAINING POLYMER | SIKA TECH AG (CH) | 2019-01-23 | — | — | EP | disclosed |
| EP-2852625-A1 | POLYMER CONTAINING SILANE GROUPS | Sika Technology AG (CH) | 2015-04-01 | — | — | EP | disclosed |
| CN-104321359-A | Polymers containing silane groups | SIKA TECHNOLOGY AG | 2015-01-28 | — | — | CN | disclosed |
| WO-2013174892-A1 | POLYMER CONTAINING SILANE GROUPS | SIKA TECHNOLOGY AG (CH) | 2013-11-28 | — | — | WO | disclosed |