Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | OGFOD1 | Q8N543 | 1/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.36 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3417899 | 0.82 | EGLN1 (0.59) | ALDH1A1LMNAHTTKMT2AOGFOD1 | |
| SCHEMBL15536589 | 0.77 | NPSR1 (0.41) | ALDH1A1KMT2AOGFOD1EGLN2EGLN1 | |
| SCHEMBL15536586 | 0.76 | C5AR1 (0.44) | ALDH1A1KMT2AOGFOD1EGLN2EGLN1 | |
| SCHEMBL15536738 | 0.75 | OGFOD1 (0.38) | ALDH1A1LMNAHTTKMT2AOGFOD1 | |
| SCHEMBL15536432 | 0.75 | NPSR1 (0.60) | ALDH1A1LMNAHTTKMT2AOGFOD1 | |
| SCHEMBL15535868 | 0.75 | NPSR1 (0.60) | ALDH1A1LMNAHTTKMT2AOGFOD1 | |
| SCHEMBL15536132 | 0.75 | NPSR1 (0.60) | ALDH1A1LMNAHTTKMT2AOGFOD1 | |
| SCHEMBL15536009 | 0.75 | EGLN3 (0.37) | ALDH1A1KMT2AOGFOD1EGLN2EGLN1 | |
| SCHEMBL15536497 | 0.74 | OGFOD1 (0.40) | ALDH1A1LMNAKMT2AOGFOD1EGLN2 | |
| SCHEMBL15536196 | 0.74 | NPSR1 (0.59) | ALDH1A1LMNAHTTKMT2AOGFOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013177478-A2 | TREATMENT METHOD | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2013-11-28 | — | — | WO | disclosed |