Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 7/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1979586 | 0.93 | AR (0.47) | ARMMP13GAA | |
| SCHEMBL18952966 | 0.91 | AR (0.36) | ARMMP13 | |
| SCHEMBL18952993 | 0.87 | AR (0.45) | ARMMP13 | |
| SCHEMBL1982669 | 0.86 | AR (0.46) | ARMMP13 | |
| SCHEMBL30939578 | 0.85 | AR (0.48) | AR | |
| SCHEMBL1978289 | 0.85 | AR (0.48) | AR | |
| SCHEMBL13720509 | 0.84 | AR (0.47) | ARMMP13 | |
| SCHEMBL1982561 | 0.83 | AR (0.47) | ARMMP13 | |
| SCHEMBL30939663 | 0.82 | AR (0.46) | ARMMP13 | |
| SCHEMBL1978546 | 0.82 | AR (0.46) | ARMMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2852588-A1 | HYDANTOIN DERIVATIVES AS KV3 INHIBITORS | Autifony Therapeutics Limited (GB) | 2015-04-01 | — | — | EP | disclosed |
| WO-2013175211-A1 | HYDANTOIN DERIVATIVES AS KV3 INHIBITORS | AUTIFONY THERAPEUTICS LIMITED (GB) | 2013-11-28 | — | — | WO | disclosed |