Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15536747 | 0.91 | AR (0.45) | ARMMP13 | |
| SCHEMBL18610521 | 0.86 | AR (0.42) | AR | |
| SCHEMBL1980366 | 0.86 | AR (0.36) | ARMMP13MEN1ALDH1A1MAPT | |
| SCHEMBL1984305 | 0.85 | SLC22A12 (0.37) | ARMMP13 | |
| SCHEMBL30939605 | 0.85 | SLC22A12 (0.37) | ARMMP13 | |
| SCHEMBL1981488 | 0.84 | AR (0.36) | ARMMP13 | |
| SCHEMBL1979251 | 0.84 | AR (0.35) | ARMMP13 | |
| SCHEMBL1979586 | 0.84 | AR (0.47) | ARMMP13 | |
| SCHEMBL1978686 | 0.83 | AR (0.40) | ARMMP13 | |
| SCHEMBL19749959 | 0.79 | AR (0.35) | ARMMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3386506-A1 | MODULATORS OF KV3 CHANNELS TO TREAT PAIN | Autifony Therapeutics Limited (GB) | 2018-10-17 | — | — | EP | disclosed |
| WO-2017098254-A1 | MODULATORS OF KV3 CHANNELS TO TREAT PAIN | AUTIFONY THERAPEUTICS LIMITED (GB) | 2017-06-15 | — | — | WO | disclosed |