Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 20/20 | 0.83 |
| ▸ | KDR | P35968 | 20/20 | 0.83 |
| ▸ | IGF1R | P08069 | 19/20 | 0.83 |
| ▸ | MST1R | Q04912 | 2/20 | 0.70 |
| ▸ | AURKA | O14965 | 1/20 | 0.68 |
| ▸ | JAK2 | O60674 | 1/20 | 0.68 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.68 |
| ▸ | ABL1 | P00519 | 1/20 | 0.68 |
| ▸ | INSR | P06213 | 1/20 | 0.68 |
| ▸ | LCK | P06239 | 1/20 | 0.68 |
| ▸ | FES | P07332 | 1/20 | 0.68 |
| ▸ | CSF1R | P07333 | 1/20 | 0.68 |
| ▸ | LYN | P07948 | 1/20 | 0.68 |
| ▸ | RET | P07949 | 1/20 | 0.68 |
| ▸ | FGR | P09769 | 1/20 | 0.68 |
| ▸ | KIT | P10721 | 1/20 | 0.68 |
| ▸ | PIM1 | P11309 | 1/20 | 0.68 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.68 |
| ▸ | SRC | P12931 | 1/20 | 0.68 |
| ▸ | PRKACA | P17612 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL783420 | 0.91 | MET (1.00) | METKDRIGF1RMST1R | |
| SCHEMBL15559333 | 0.90 | MET (0.83) | METKDRIGF1RMST1RAURKA | |
| SCHEMBL198584 | 0.85 | MET (1.00) | METKDRIGF1RMST1R | |
| SCHEMBL196661 | 0.85 | MET (0.85) | METKDRIGF1RMST1RAURKA | |
| SCHEMBL15549540 | 0.84 | MET (0.77) | METKDRIGF1RMST1RAURKA | |
| SCHEMBL198400 | 0.84 | MET (1.00) | METKDRIGF1RMST1R | |
| SCHEMBL201049 | 0.84 | MET (0.87) | METKDRIGF1RMST1R | |
| SCHEMBL197924 | 0.84 | IGF1R (1.00) | METKDRIGF1RMST1RAURKA | |
| SCHEMBL197413 | 0.84 | MET (1.00) | METKDRIGF1RMST1R | |
| SCHEMBL199470 | 0.84 | MET (0.87) | METKDRIGF1RMST1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013180949-A1 | SUBSTITUTED QUINOLINE COMPOUNDS AND METHODS OF USE | XI NING (US) | 2013-12-05 | — | — | WO | disclosed |