Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 6/20 | 0.55 |
| ▸ | PROKR1 | Q8TCW9 | 6/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RBP4 | P02753 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15537089 | 0.87 | FPR2 (0.56) | FPR2PROKR1FFAR4KDM4EMAPK1 | |
| SCHEMBL19921923 | 0.85 | FPR2 (0.51) | FPR2PROKR1KDM4EALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL28086957 | 0.79 | FPR2 (0.55) | FPR2PROKR1KDM4EALDH1A1MAPT | |
| SCHEMBL15537095 | 0.77 | FPR2 (0.53) | FPR2PROKR1FFAR4ALDH1A1MEN1 | |
| SCHEMBL3933536 | 0.77 | FPR2 (0.46) | FPR2PROKR1FFAR4KDM4ERBP4 | |
| SCHEMBL28122531 | 0.74 | NPC1 (0.42) | KDM4EALDH1A1MAPTRAB9AMEN1 | |
| SCHEMBL19941299 | 0.73 | FPR2 (0.46) | FPR2PROKR1FFAR4KDM4EMAPK1 | |
| SCHEMBL30027758 | 0.73 | FPR2 (0.52) | FPR2PROKR1KDM4EALDH1A1RAB9A | |
| SCHEMBL16657604 | 0.73 | FPR2 (0.52) | FPR2PROKR1KDM4EALDH1A1RAB9A | |
| SCHEMBL1094025 | 0.73 | KDM4E (0.54) | FFAR4KDM4ERBP4MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2855449-A1 | SULFONYL PIPERIDINE DERIVATIVES AND THEIR USE FOR TREATING PROKINETICIN MEDIATED DISEASES | Takeda Pharmaceutical Company Limited (JP) | 2015-04-08 | — | — | EP | disclosed |
| WO-2013179024-A1 | SULFONYL PIPERIDINE DERIVATIVES AND THEIR USE FOR TREATING PROKINETICIN MEDIATED DISEASES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-12-05 | — | — | WO | disclosed |