SCHEMBL15537352

SCHEMBL15537352

CC(CC(C)(O)C(=O)c1ccc(Cc2ccc(C(=O)C(C)(C)O)cc2)cc1)C(Cc1ccccc1)(C(=O)c1ccc(N2CCOCC2)cc1)N(C)C

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.38
RORC P51449 5/20 0.37
L3MBTL1 Q9Y468 2/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
MAPT P10636 3/20 0.35
SLC13A5 Q86YT5 1/20 0.35
MAOB P27338 1/20 0.34
ALDH1A1 P00352 2/20 0.34
AOC3 Q16853 2/20 0.34
PIK3CD O00329 1/20 0.34
PIK3CA P42336 1/20 0.34
PIK3CB P42338 1/20 0.34
PIK3CG P48736 1/20 0.34
PRKDC P78527 1/20 0.34
LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30955710 0.83 SMN1; SMN2 (0.45) SMN1; SMN2RORCL3MBTL1MEN1KMT2A
SCHEMBL537644 0.81 MEN1 (0.47) SMN1; SMN2RORCL3MBTL1MEN1KMT2A
SCHEMBL1042623 0.81 SMN1; SMN2 (0.46) SMN1; SMN2RORCL3MBTL1MEN1KMT2A
SCHEMBL1221775 0.78 SMN1; SMN2 (0.39) SMN1; SMN2RORCL3MBTL1MEN1KMT2A
SCHEMBL29242697 0.77 MAPT (0.40) SMN1; SMN2RORCL3MBTL1MEN1KMT2A
SCHEMBL7804774 0.76 SMN1; SMN2 (0.43) SMN1; SMN2L3MBTL1MEN1KMT2AMAPT
SCHEMBL8900160 0.76 SMN1; SMN2 (0.43) SMN1; SMN2RORCL3MBTL1MEN1KMT2A
SCHEMBL7532538 0.75 ALDH1A1 (0.45) SMN1; SMN2RORCL3MBTL1MEN1KMT2A
SCHEMBL2774235 0.74 SMN1; SMN2 (0.50) SMN1; SMN2RORCL3MBTL1MEN1KMT2A
SCHEMBL1043533 0.74 NPC1 (0.46) SMN1; SMN2L3MBTL1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8940804-B2 Acrylate-based UV-curable ink, method and an ink base for producing same PELIKAN HARDCOPY PRODUCTION AG (CH) 2015-01-27 US claimed
EP-2855553-B1 RADIATION-CURABLE COMPOUNDS BASF SE (DE) 2017-03-01 EP disclosed
EP-3004199-A1 METHOD FOR PRODUCING URETHANE (METH)ACRYLATES BASF SE (DE) 2016-04-13 EP disclosed
EP-2855553-A1 RADIATION-CURABLE COMPOUNDS BASF SE (DE) 2015-04-08 EP disclosed
WO-2014191235-A1 METHOD FOR PRODUCING URETHANE (METH)ACRYLATES BASF SE (DE) 2014-12-04 WO disclosed
WO-2013178523-A1 RADIATION-CURABLE COMPOUNDS BASF SE (DE) 2013-12-05 WO disclosed