Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 1/20 | 0.54 |
| ▸ | DPP4 | P27487 | 1/20 | 0.52 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.49 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.48 |
| ▸ | FPR2 | P25090 | 2/20 | 0.48 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.48 |
| ▸ | STS | P08842 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4239855 | 0.88 | DPP4 (0.54) | DPP4GPR119KDM4EPKMMEN1 | |
| SCHEMBL20971728 | 0.87 | DPP4 (0.53) | DPP4GPR119KDM4EPKMKMT2A | |
| SCHEMBL20971782 | 0.87 | STS (0.48) | CCR3GPR119STSKDM4EPKM | |
| SCHEMBL19067521 | 0.85 | KDM4E (0.51) | DPP4GPR119KDM4EPKMMEN1 | |
| SCHEMBL28540034 | 0.85 | DPP4 (0.51) | DPP4GPR119STSKDM4EPKM | |
| SCHEMBL5214882 | 0.85 | EPHX2 (0.57) | DPP4GPR119STSMEN1KMT2A | |
| SCHEMBL20971865 | 0.85 | USP30 (0.48) | CCR3DPP4GPR119USP30CYP3A4 | |
| SCHEMBL22265941 | 0.84 | DPP4 (0.56) | DPP4GPR119STSKDM4EPKM | |
| SCHEMBL20971822 | 0.84 | GPR119 (0.54) | DPP4GPR119KDM4EPKM | |
| SCHEMBL16825244 | 0.83 | GPR119 (0.60) | DPP4GPR119STSKDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2855449-A1 | SULFONYL PIPERIDINE DERIVATIVES AND THEIR USE FOR TREATING PROKINETICIN MEDIATED DISEASES | Takeda Pharmaceutical Company Limited (JP) | 2015-04-08 | — | — | EP | disclosed |
| WO-2013179024-A1 | SULFONYL PIPERIDINE DERIVATIVES AND THEIR USE FOR TREATING PROKINETICIN MEDIATED DISEASES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-12-05 | — | — | WO | disclosed |