Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 5/20 | 0.41 |
| ▸ | GYS1 | P13807 | 9/20 | 0.40 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15539344 | 1.00 | SCN9A (0.42) | SCN9ACNR2GYS1SPHK2SPHK1 | |
| SCHEMBL15540341 | 0.98 | CNR2 (0.41) | SCN9ACNR2GYS1SPHK2SPHK1 | |
| SCHEMBL15540092 | 0.98 | CNR2 (0.41) | SCN9ACNR2GYS1SPHK2SPHK1 | |
| SCHEMBL15540077 | 0.98 | CNR2 (0.41) | SCN9ACNR2GYS1SPHK2SPHK1 | |
| SCHEMBL15539341 | 0.93 | SCN9A (0.41) | SCN9ACNR2GYS1SPHK2SPHK1 | |
| SCHEMBL16758139 | 0.92 | SCN9A (0.42) | SCN9ACNR2GYS1SPHK2SPHK1 | |
| SCHEMBL15539098 | 0.91 | PDK2 (0.42) | SCN9ACNR2SPHK2SPHK1PDK2 | |
| SCHEMBL15540030 | 0.90 | CNR2 (0.39) | SCN9ACNR2GYS1SPHK2SPHK1 | |
| SCHEMBL15539405 | 0.89 | CNR2 (0.43) | SCN9ACNR2 | |
| SCHEMBL15537620 | 0.89 | CNR2 (0.41) | SCN9ACNR2SPHK2SPHK1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858986-A1 | PIPERIDINE DERIVATIVES FOR GPR119 AGONIST | Chong Kun Dang Pharmaceutical Corp. (KR) | 2015-04-15 | — | — | EP | disclosed |
| WO-2013187646-A1 | PIPERIDINE DERIVATIVES FOR GPR119 AGONIST | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2013-12-19 | — | — | WO | disclosed |