SCHEMBL15539658

SCHEMBL15539658

C[C@H](O)[C@@H](O)CCc1cccc(O[Si](C)(C)C(C)(C)C)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.36
CA12 O43570 4/20 0.35
CA1 P00915 4/20 0.35
CA9 Q16790 4/20 0.35
HSP90AA1 P07900 1/20 0.34
HSP90AB1 P08238 1/20 0.34
GABRA1 P14867 1/20 0.34
GABRG2 P18507 1/20 0.34
GABRB3 P28472 1/20 0.34
GABRA3 P34903 1/20 0.34
GABRA2 P47869 1/20 0.34
GABRB2 P47870 1/20 0.34
PPARG P37231 2/20 0.34
PPARA Q07869 2/20 0.34
CYSLTR2 Q9NS75 1/20 0.34
CYSLTR1 Q9Y271 1/20 0.34
CHRM2 P08172 1/20 0.33
CHRM1 P11229 1/20 0.33
CHRM3 P20309 1/20 0.33
CYP2D6 P10635 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15540394 1.00 TAAR1 (0.36) TAAR1CA12CA1CA9HSP90AA1
SCHEMBL2635979 0.80 CYP4F2 (0.50) TAAR1CA12CA1CA9HSP90AA1
SCHEMBL6171672 0.80 MTNR1A (0.38) HSP90AA1HSP90AB1PPARGPPARA
SCHEMBL19745618 0.79 CA12 (0.40) TAAR1CA12CA1CA9HSP90AA1
SCHEMBL15540390 0.78 TAAR1 (0.38) TAAR1CA12CA1CA9HSP90AA1
SCHEMBL15539654 0.78 TAAR1 (0.38) TAAR1CA12CA1CA9HSP90AA1
SCHEMBL5530316 0.77 CA12 (0.39) TAAR1CA12CA1CA9HSP90AA1
SCHEMBL6362546 0.77 TAAR1 (0.58) TAAR1CA12CA1CA9
SCHEMBL29851528 0.77 KDR (0.41) TAAR1CA12CA1CA9HSP90AA1
SCHEMBL559965 0.77 KDR (0.41) TAAR1CA12CA1CA9HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2861571-A1 PHENYLALKYL SULFAMATE COMPOUND AND MUSCLE RELAXANT COMPOSITION COMPRISING THE SAME Bio-Pharm Solutions Co., Ltd. (KR) 2015-04-22 EP disclosed
WO-2013187727-A1 PHENYLALKYL SULFAMATE COMPOUND AND MUSCLE RELAXANT COMPOSITION COMPRISING THE SAME BIO-PHARM SOLUTIONS CO., LTD. (KR) 2013-12-19 WO disclosed