Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 5/20 | 0.58 |
| ▸ | HRH1 | P35367 | 4/20 | 0.58 |
| ▸ | HTR2A | P28223 | 4/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.58 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.58 |
| ▸ | ESR1 | P03372 | 1/20 | 0.58 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | HRH2 | P25021 | 1/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.58 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.58 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15540631 | 1.00 | OPRK1 (0.58) | OPRK1HRH1HTR2ACHRM2CHRM1 | |
| Diisopromine SCHEMBL25648 | 0.85 | HRH1 (0.63) | OPRK1HRH1HTR2ACHRM2CHRM1 | |
| Diisopromine SCHEMBL11582569 | 0.83 | HRH1 (0.61) | OPRK1HRH1HTR2ACHRM2CHRM1 | |
| SCHEMBL9221429 | 0.81 | CHRM3 (0.65) | OPRK1HRH1HTR2ACHRM2CHRM1 | |
| SCHEMBL5614313 | 0.81 | CHRM3 (0.65) | OPRK1HRH1HTR2ACHRM2CHRM1 | |
| SCHEMBL2473562 | 0.81 | CHRM3 (0.78) | OPRK1HRH1HTR2ACHRM2CHRM1 | |
| SCHEMBL2473559 | 0.81 | CHRM3 (0.78) | OPRK1HRH1HTR2ACHRM2CHRM1 | |
| SCHEMBL5408822 | 0.80 | CHRM3 (0.64) | OPRK1HRH1HTR2ACHRM2CHRM1 | |
| SCHEMBL19982630 | 0.80 | HRH1 (0.50) | OPRK1HRH1HTR2ACHRM2CHRM1 | |
| SCHEMBL9230264 | 0.77 | CHRM3 (0.64) | OPRK1HRH1HTR2ACHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2760822-A1 | DESFESOTERODINE SALTS | Ratiopharm GmbH (DE) | 2014-08-06 | — | — | EP | disclosed |
| WO-2013188829-A1 | DESFESOTERODINE SALTS | RATIOPHARM GMBH (DE) | 2013-12-19 | — | — | WO | disclosed |