Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | GAA | P10253 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17265438 | 0.89 | NR4A1 (0.53) | NR4A1ALDH1A1HTTALDH1A3MAPT | |
| SCHEMBL29989590 | 0.88 | ALDH1A1 (0.65) | NR4A1ALDH1A1HTTALDH1A3MAPT | |
| SCHEMBL15358685 | 0.87 | NR4A1 (0.61) | NR4A1ALDH1A1HTTALDH1A3MAPT | |
| SCHEMBL15244065 | 0.86 | NR4A1 (0.50) | NR4A1ALDH1A1HTTALDH1A3MAPT | |
| SCHEMBL13723401 | 0.86 | NR4A1 (0.50) | NR4A1ALDH1A1HTTALDH1A3MAPT | |
| SCHEMBL25190349 | 0.85 | NR4A1 (0.47) | NR4A1ALDH1A1HTTALDH1A3MAPT | |
| SCHEMBL30336504 | 0.85 | NR4A1 (0.47) | NR4A1ALDH1A1HTTALDH1A3MAPT | |
| SCHEMBL5395255 | 0.85 | NR4A1 (0.49) | NR4A1ALDH1A1HTTALDH1A3MAPT | |
| SCHEMBL10035924 | 0.84 | NR4A1 (0.48) | NR4A1ALDH1A1HTTALDH1A3MAPT | |
| SCHEMBL29399632 | 0.84 | NR4A1 (0.48) | NR4A1ALDH1A1HTTALDH1A3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013188856-A1 | IMIDAZOPYRAZINE SYK INHIBITORS | GILEAD CONNECTICUT, INC. (US) | 2013-12-19 | — | — | WO | disclosed |