Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 4/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.30 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.30 |
| ▸ | OTUD7B | Q6GQQ9 | 2/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15543479 | 0.91 | FASN (0.48) | FASNLTA4HAKT1HSD11B1OPRM1 | |
| SCHEMBL15543310 | 0.89 | FASN (0.48) | FASNLTA4HSSTR5OPRM1SIGMAR1 | |
| SCHEMBL15544217 | 0.89 | FASN (0.48) | FASNLTA4HOPRM1SIGMAR1 | |
| SCHEMBL15582343 | 0.89 | FASN (0.38) | FASNHSD11B1 | |
| SCHEMBL15544250 | 0.87 | FASN (0.47) | FASNLTA4HSSTR5MTOR | |
| SCHEMBL15543586 | 0.87 | FASN (0.63) | FASNOPRM1SIGMAR1 | |
| SCHEMBL14842144 | 0.83 | FASN (0.45) | FASNHSD11B1CCNA2CDK2CDK5 | |
| SCHEMBL15543780 | 0.81 | FASN (0.51) | FASNSSTR5HSD11B1OPRM1SIGMAR1 | |
| SCHEMBL15543895 | 0.80 | FASN (0.49) | FASNLTA4HSSTR5OPRM1SIGMAR1 | |
| SCHEMBL15543457 | 0.80 | FASN (0.49) | FASNSSTR5HSD11B1OPRM1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014008223-A2 | FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2014-01-09 | — | — | WO | claimed |
| WO-2014008223-A2 | FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2014-01-09 | — | — | WO | disclosed |
| WO-2014008223-A2 | FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2014-01-09 | — | — | WO | disclosed |