Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 8/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15544329 | 0.90 | GRIN1 (0.33) | GRIN2BGRIN1 | |
| SCHEMBL15543527 | 0.82 | FASN (0.30) | — | |
| SCHEMBL15556001 | 0.81 | CTSK (0.31) | — | |
| SCHEMBL15543841 | 0.78 | FASN (0.38) | CYP1A2 | |
| SCHEMBL15543695 | 0.78 | FASN (0.39) | — | |
| SCHEMBL15543968 | 0.74 | CHRM1 (0.40) | — | |
| SCHEMBL15544962 | 0.73 | FASN (0.38) | — | |
| SCHEMBL15544262 | 0.72 | FASN (0.35) | — | |
| SCHEMBL15545040 | 0.71 | FFAR4 (0.35) | — | |
| SCHEMBL15543596 | 0.69 | FASN (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014008223-A2 | FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2014-01-09 | — | — | WO | disclosed |