Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | ALPI | P09923 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | TTR | P02766 | 4/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27860085 | 0.91 | CYP19A1 (0.51) | MAPTKDM4EPOLBALPIGAA | |
| SCHEMBL2781916 | 0.86 | MAPT (0.71) | MAPTKDM4EPOLBALPIGAA | |
| SCHEMBL1508800 | 0.85 | CYP19A1 (0.64) | MAPTKDM4EPOLBALPIGAA | |
| SCHEMBL349721 | 0.85 | CYP19A1 (0.62) | MAPTKDM4EPOLBALPIGAA | |
| SCHEMBL5084379 | 0.80 | PTPN1 (0.51) | MAPTKDM4EPOLBGAARECQL | |
| SCHEMBL2319144 | 0.79 | CYP19A1 (0.68) | MAPTKDM4EPOLBALPIGAA | |
| SCHEMBL17318042 | 0.79 | CYP1A1 (0.67) | MAPTATMCYP19A1CYP3A4CYP1A1 | |
| SCHEMBL7200859 | 0.79 | CYP1A1 (0.67) | MAPTATMCYP19A1CYP3A4CYP1A1 | |
| SCHEMBL677661 | 0.78 | CYP19A1 (0.63) | CYP19A1CYP3A4ARESR2TUBB4A | |
| SCHEMBL910349 | 0.77 | PTPN1 (0.60) | CYP1A1CYP1B1TP53PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240263203-A1 | RECOMBINANT HOST CELLS WITH IMPROVED PRODUCTION OF TETRAKETIDE DERIVATIVES | IPTECTOR ASSETS APS (DK) | 2024-08-08 | — | — | US | disclosed |
| US-20220257561-A1 | COMPOSITIONS AND METHODS FOR IMPROVING WELLNESS | ADVANCED DELIVERY LABS LLC (US) | 2022-08-18 | — | — | US | disclosed |
| EP-3906301-A1 | RECOMBINANT HOST CELLS WITH IMPROVED PRODUCTION OF TETRAKETIDE DERIVATIVES | Barrit Sarl (FR) | 2021-11-10 | — | — | EP | disclosed |
| WO-2020141230-A1 | RECOMBINANT HOST CELLS WITH IMPROVED PRODUCTION OF TETRAKETIDE DERIVATIVES | BARRIT SARL (FR) | 2020-07-09 | — | — | WO | disclosed |
| WO-2014007853-A1 | DIHYDROMYRICETIN FOR THE TREATMENT OF DISEASES AND DISORDERS OF THE GLUTAMATERGIC SYSTEM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-01-09 | — | — | WO | disclosed |