Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.67 |
| ▸ | CYP19A1 | P11511 | 10/20 | 0.61 |
| ▸ | MAOB | P27338 | 6/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | TAS2R31 | P59538 | 1/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7200859 | 1.00 | CYP1A1 (0.67) | CYP1A1CYP1A2CYP1B1CYP19A1MAOB | |
| SCHEMBL773767 | 0.89 | CYP19A1 (0.66) | CYP1A1CYP1A2CYP1B1CYP19A1MAOB | |
| SCHEMBL349721 | 0.87 | CYP19A1 (0.62) | CYP1A1CYP1A2CYP1B1CYP19A1MAOB | |
| SCHEMBL5084282 | 0.86 | ABCG2 (0.68) | CYP1A1CYP1A2CYP1B1CYP19A1MAOB | |
| SCHEMBL6509053 | 0.85 | CYP1A1 (0.68) | CYP1A1CYP1A2CYP1B1CYP19A1CYP3A4 | |
| SCHEMBL2319144 | 0.85 | CYP19A1 (0.68) | CYP1A1CYP1A2CYP1B1CYP19A1CYP3A4 | |
| SCHEMBL1508800 | 0.84 | CYP19A1 (0.64) | CYP1A1CYP1A2CYP1B1CYP19A1MAOB | |
| SCHEMBL2781916 | 0.82 | MAPT (0.71) | CYP1A1CYP1A2CYP1B1CYP19A1CYP3A4 | |
| SCHEMBL5084379 | 0.81 | PTPN1 (0.51) | CYP1A1CYP1A2CYP1B1CYP19A1CYP3A4 | |
| SCHEMBL27860085 | 0.81 | CYP19A1 (0.51) | CYP1A1CYP1A2CYP1B1CYP19A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170189372-A1 | USE OF SUBSTITUTED CHROMAN COMPOUNDS | INSTYTUT BIOLOGII MEDYCZNEJ (PL) | 2017-07-06 | — | — | US | claimed |
| EP-3148527-A1 | USE OF SUBSTITUTED CHROMAN COMPOUNDS | Instytut Biologii Medycznej Polskiej Akademii Nauk (PL) | 2017-04-05 | — | — | EP | claimed |
| WO-2015185515-A1 | USE OF SUBSTITUTED CHROMAN COMPOUNDS | INSTYTUT BIOLOGII MEDYCZNEJ (PL) | 2015-12-10 | — | — | WO | claimed |
| US-20170189372-A1 | USE OF SUBSTITUTED CHROMAN COMPOUNDS | INSTYTUT BIOLOGII MEDYCZNEJ (PL) | 2017-07-06 | — | — | US | disclosed |
| EP-3148527-A1 | USE OF SUBSTITUTED CHROMAN COMPOUNDS | Instytut Biologii Medycznej Polskiej Akademii Nauk (PL) | 2017-04-05 | — | — | EP | disclosed |
| WO-2015185515-A1 | USE OF SUBSTITUTED CHROMAN COMPOUNDS | INSTYTUT BIOLOGII MEDYCZNEJ (PL) | 2015-12-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170189372-A1 | USE OF SUBSTITUTED CHROMAN COMPOUNDS | CHRM1, C5, THRB | CYP1A1 168/4885CYP1A2 322/4885CYP1B1 161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.