Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 10/20 | 0.49 |
| ▸ | BACE1 | P56817 | 10/20 | 0.49 |
| ▸ | BCHE | P06276 | 8/20 | 0.49 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17606641 | 0.82 | ACHE (0.50) | ACHEBACE1BCHEDPP7MEN1 | |
| Hydrochloric Acid SCHEMBL9717982 | 0.81 | ACHE (0.49) | ACHEBACE1BCHEDPP7MEN1 | |
| Hydrochloric Acid SCHEMBL9178350 | 0.81 | ACHE (0.49) | ACHEBACE1BCHEDPP7MEN1 | |
| SCHEMBL4542372 | 0.79 | ACHE (0.56) | ACHEBACE1BCHEDPP7MEN1 | |
| SCHEMBL9230559 | 0.78 | POLB (0.50) | ACHEBACE1BCHEDPP7MEN1 | |
| SCHEMBL9717983 | 0.77 | ACHE (0.44) | ACHEBACE1BCHEDPP7MEN1 | |
| SCHEMBL1965410 | 0.76 | OPRL1 (0.55) | MEN1KMT2AOPRL1SIGMAR1POLB | |
| SCHEMBL4533504 | 0.74 | ACHE (0.47) | ACHEBACE1BCHEDPP7MEN1 | |
| SCHEMBL12445301 | 0.74 | CYP3A4 (0.54) | MEN1KMT2AOPRL1SIGMAR1POLB | |
| SCHEMBL20664069 | 0.72 | KDM1A (0.58) | ACHEBACE1BCHEDPP7KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014008223-A2 | FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2014-01-09 | — | — | WO | disclosed |