Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | ENPP2 | Q13822 | 9/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.35 |
| ▸ | FUT8 | Q9BYC5 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GRK2 | P25098 | 1/20 | 0.33 |
| ▸ | PLEC | Q15149 | 1/20 | 0.33 |
| ▸ | CD40 | P25942 | 1/20 | 0.33 |
| ▸ | CD40LG | P29965 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL15544707 | 0.99 | THRB (0.63) | THRBENPP2CARM1PRMT1FUT8 | |
| Lithium Ion SCHEMBL29886706 | 0.97 | THRB (0.66) | THRBENPP2CARM1PRMT1FUT8 | |
| Lithium Ion SCHEMBL15544703 | 0.94 | THRB (0.60) | THRBENPP2CARM1PRMT1FUT8 | |
| SCHEMBL18832713 | 0.92 | THRB (0.53) | THRBENPP2CARM1PRMT1FUT8 | |
| SCHEMBL13880589 | 0.92 | THRB (0.53) | THRBENPP2CARM1PRMT1FUT8 | |
| SCHEMBL12053477 | 0.85 | THRB (0.46) | THRBENPP2FUT8 | |
| SCHEMBL14388839 | 0.81 | THRB (0.56) | THRBENPP2CARM1PRMT1FUT8 | |
| SCHEMBL14388755 | 0.80 | THRB (0.54) | THRBENPP2PRMT1FUT8MEN1 | |
| SCHEMBL14388939 | 0.79 | THRB (0.55) | THRBENPP2CARM1PRMT1FUT8 | |
| SCHEMBL109532 | 0.79 | THRB (1.00) | THRBENPP2CARM1PRMT1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2877538-B1 | HOME FABRIC DYE PRODUCT | HENKEL AG & CO KGAA (DE) | 2017-09-06 | — | — | EP | claimed |
| EP-2877538-A1 | HOME FABRIC DYE PRODUCT | Punch Industries (IE) | 2015-06-03 | — | — | EP | claimed |
| WO-2014006132-A1 | HOME FABRIC DYE PRODUCT | PUNCH INDUSTRIES (IE) | 2014-01-09 | — | — | WO | claimed |
| EP-3390708-B1 | CONSUMER UNIT FOR DYEING TEXTILE | HENKEL AG & CO KGAA (DE) | 2023-04-05 | — | — | EP | disclosed |
| EP-3390708-A1 | CONSUMER UNIT FOR DYEING TEXTILE | Henkel AG & Co. KGaA (DE) | 2018-10-24 | — | — | EP | disclosed |
| EP-2877538-B1 | HOME FABRIC DYE PRODUCT | HENKEL AG & CO KGAA (DE) | 2017-09-06 | — | — | EP | disclosed |
| WO-2017102314-A1 | CONSUMER UNIT FOR DYEING TEXTILE | HENKEL AG & CO. KGAA (DE) | 2017-06-22 | — | — | WO | disclosed |
| EP-2877538-A1 | HOME FABRIC DYE PRODUCT | Punch Industries (IE) | 2015-06-03 | — | — | EP | disclosed |
| WO-2014006132-A1 | HOME FABRIC DYE PRODUCT | PUNCH INDUSTRIES (IE) | 2014-01-09 | — | — | WO | disclosed |