SCHEMBL15544932

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL211976	0.86	ALDH1A1 (0.43)	TAAR1ALDH1A1KDM4EKMT2ACYP1A1
	SCHEMBL3776543	0.86	TAAR1 (0.61)	TAAR1ALDH1A1KDM1AMAOAMAOB
	SCHEMBL16693753	0.83	TAAR1 (0.53)	TAAR1HCRTR1HCRTR2TRAP1HSP90B1
	SCHEMBL4678875	0.82	NQO1 (0.34)	TAAR1MAPTCPS1KDM4E
	SCHEMBL4677635	0.82	KDR (0.37)	TAAR1HTTKDM4ELMNACYP1A2
	SCHEMBL4682530	0.80	SLC6A4 (0.39)	TAAR1HTTKDM4ELMNACYP1A2
	SCHEMBL4678195	0.80	HTT (0.36)	ALDH1A1MAPTHTTKMT2ACYP1A2
	SCHEMBL21082219	0.79	TAAR1 (0.49)	TAAR1HCRTR1HCRTR2TRAP1HSP90B1
	SCHEMBL4677644	0.78	HTT (0.44)	HTTRAB9AKDM4E
	SCHEMBL14992582	0.77	TAAR1 (0.47)	TAAR1HCRTR1HCRTR2TRAP1HSP90B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.