Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.43 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM6B | O15054 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | KDM5C | P41229 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL5534135 | 0.88 | EHMT2 (0.48) | POLBEHMT2EHMT1APOBEC3GHPGD | |
| SCHEMBL16254246 | 0.88 | EHMT2 (0.42) | POLBEHMT2EHMT1APOBEC3GHPGD | |
| SCHEMBL20072028 | 0.85 | ALDH1A1 (0.42) | EHMT2EHMT1APOBEC3GHPGDHSD17B10 | |
| SCHEMBL29523202 | 0.85 | EHMT2 (0.55) | POLBEHMT2EHMT1APOBEC3GHPGD | |
| SCHEMBL14868078 | 0.82 | EHMT2 (0.52) | POLBEHMT2EHMT1APOBEC3GHPGD | |
| SCHEMBL14872084 | 0.81 | EHMT2 (0.50) | EHMT2EHMT1APOBEC3GHPGDHSD17B10 | |
| SCHEMBL29267318 | 0.80 | ALDH1A1 (0.36) | POLBEHMT2EHMT1APOBEC3GHPGD | |
| SCHEMBL21761321 | 0.79 | EHMT2 (0.44) | POLBEHMT2EHMT1APOBEC3GHPGD | |
| SCHEMBL2558340 | 0.79 | EHMT2 (0.44) | EHMT2EHMT1APOBEC3GHPGDHSD17B10 | |
| SCHEMBL29386113 | 0.78 | MAPT (0.36) | POLBEHMT2EHMT1APOBEC3GHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113039191-B | Nucleotide analogues | 奇异基因组学系统公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-113039191-A | Nucleotide analogs | 奇异基因组学系统公司 | 2021-06-25 | — | — | CN | disclosed |
| EP-3270903-B1 | DISULFIDE-CONTAINING ALKYNE LINKING AGENTS | ARROWHEAD PHARMACEUTICALS INC (US) | 2020-05-06 | — | — | EP | disclosed |
| US-20180023084-A1 | Disulfide-Containing Alkyne Linking Agents | SIXTH STREETLENDING PARTNERS, AS THE ADMINISTRATIVE AGENT | 2018-01-25 | — | — | US | disclosed |
| US-9803201-B2 | Disulfide-containing alkyne linking agents | Arrowhead Pharmaceuticals, Inc. (US) | 2017-10-31 | — | — | US | disclosed |
| US-20160272971-A1 | Disulfide-Containing Alkyne Linking Agents | SIXTH STREETLENDING PARTNERS, AS THE ADMINISTRATIVE AGENT | 2016-09-22 | — | — | US | disclosed |
| EP-2928503-A1 | AURISTATIN COMPOUNDS AND CONJUGATES THEREOF | Mersana Therapeutics, Inc. (US) | 2015-10-14 | — | — | EP | disclosed |
| WO-2014093379-A1 | AURISTATIN COMPOUNDS AND CONJUGATES THEREOF | MERSANA THERAPEUTICS, INC. (US) | 2014-06-19 | — | — | WO | disclosed |
| WO-2014008375-A1 | TERMINALLY MODIFIED POLYMERS AND CONJUGATES THEREOF | MERSANA THERAPEUTICS, INC. (US) | 2014-01-09 | — | — | WO | disclosed |