Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 6/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2722264 | 0.98 | MEN1 (0.48) | EPHX2MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL8958406 | 0.88 | SMN1; SMN2 (0.48) | EPHX2MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL9468149 | 0.87 | TSHR (0.46) | EPHX2MEN1KMT2ASMN1; SMN2ACHE | |
| SCHEMBL8958557 | 0.85 | MEN1 (0.52) | EPHX2MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL9447837 | 0.85 | MEN1 (0.52) | EPHX2MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL18173574 | 0.85 | MEN1 (0.52) | EPHX2MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL8958401 | 0.85 | MEN1 (0.52) | EPHX2MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL8958237 | 0.85 | MEN1 (0.52) | EPHX2MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL31618226 | 0.85 | TSHR (0.45) | EPHX2SMN1; SMN2ACHE | |
| SCHEMBL15532776 | 0.84 | MEN1 (0.48) | EPHX2MEN1KMT2ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2875001-A1 | NITROGENOUS HETEROCYCLIC DERIVATIVES AND THEIR APPLICATION IN DRUGS | Sunshine Lake Pharma Co., Ltd. (CN) | 2015-05-27 | — | — | EP | disclosed |
| WO-2014012360-A1 | NITROGENOUS HETEROCYCLIC DERIVATIVES AND THEIR APPLICATION IN DRUGS | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2014-01-23 | — | — | WO | disclosed |