Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4046195 | 0.85 | PARP1 (1.00) | PARP1CYP1A2 | |
| SCHEMBL15532419 | 0.85 | PARP1 (0.75) | PARP1CYP1A2 | |
| SCHEMBL30461662 | 0.85 | PARP1 (0.75) | PARP1CYP1A2 | |
| SCHEMBL4052397 | 0.83 | PARP1 (0.94) | PARP1CYP1A2 | |
| SCHEMBL25420566 | 0.77 | PARP1 (0.62) | PARP1CYP1A2 | |
| SCHEMBL16641855 | 0.77 | PARP1 (0.62) | PARP1 | |
| SCHEMBL16641854 | 0.76 | PARP1 (0.60) | PARP1CYP1A2 | |
| SCHEMBL4047260 | 0.75 | PARP1 (0.80) | PARP1CYP1A2 | |
| SCHEMBL5495907 | 0.75 | PARP1 (0.79) | PARP1CYP1A2 | |
| SCHEMBL4047902 | 0.73 | PARP1 (0.76) | PARP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2861597-A1 | SUBSTITUTED PYRAZOLOQUINAZOLINONES AND PYRROLOQUINAZOLINONES AS ALLOSTERIC MODULATORS OF GROUP II METABOTROPIC GLUTAMATE RECEPTORS | Domain Therapeutics (FR) | 2015-04-22 | — | — | EP | disclosed |
| WO-2014007405-A9 | METHOD FOR PRODUCING AROMATIC COMPOUND | 住友化学株式会社 (JP) | 2014-02-27 | — | — | WO | disclosed |
| WO-2014007405-A1 | METHOD FOR PRODUCING AROMATIC COMPOUND | 住友化学株式会社 (JP) | 2014-01-09 | — | — | WO | disclosed |
| WO-2013174822-A1 | SUBSTITUTED PYRAZOLOQUINAZOLINONES AND PYRROLOQUINAZOLINONES AS ALLOSTERIC MODULATORS OF GROUP II METABOTROPIC GLUTAMATE RECEPTORS | DOMAIN THERAPEUTICS (FR) | 2013-11-28 | — | — | WO | disclosed |