⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2371298 | 0.83 | TSHR (0.46) | — | |
| SCHEMBL5174528 | 0.83 | TSHR (0.46) | — | |
| SCHEMBL2371285 | 0.83 | TSHR (0.46) | — | |
| SCHEMBL5304841 | 0.80 | — | — | |
| SCHEMBL250433 | 0.74 | — | — | |
| SCHEMBL20490085 | 0.74 | — | — | |
| SCHEMBL27504901 | 0.72 | PPARG (0.32) | — | |
| SCHEMBL458096 | 0.70 | — | — | |
| SCHEMBL1838652 | 0.70 | — | — | |
| SCHEMBL3389521 | 0.67 | HMGCR (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230130617-A1 | PROCESS FOR IMPROVED OPIOID SYNTHESIS | RHODES TECHNOLOGIES (US) | 2023-04-27 | — | — | US | disclosed |
| US-10316042-B2 | Process for improved opioid synthesis | RHODES TECHNOLOGIES (US) | 2019-06-11 | — | — | US | disclosed |
| EP-2872516-B1 | PROCESS FOR IMPROVED OPIOID SYNTHESIS | RHODES TECH (US) | 2017-08-30 | — | — | EP | disclosed |
| US-20150315203-A1 | PROCESS FOR IMPROVED OPIOID SYNTHESIS | RHODES TECHNOLOGIES | 2015-11-05 | — | — | US | disclosed |
| EP-2872516-A1 | PROCESS FOR IMPROVED OPIOID SYNTHESIS | Rhodes Technologies (US) | 2015-05-20 | — | — | EP | disclosed |
| WO-2014013313-A1 | PROCESS FOR IMPROVED OPIOID SYNTHESIS | RHODES TECHNOLOGIES (US) | 2014-01-23 | — | — | WO | disclosed |