SCHEMBL2371285

SCHEMBL2371285

C=C/C=C/[C]=C/CCCCCCCCC

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.46
ALDH1A1 P00352 2/20 0.34
FAAH O00519 2/20 0.33
ABCG2 Q9UNQ0 2/20 0.33
TRPV1 Q8NER1 1/20 0.33
PTGS1 P23219 1/20 0.33
PPARG P37231 1/20 0.33
OPRK1 P41145 1/20 0.33
THRB P10828 1/20 0.32
HMGCR P04035 2/20 0.32
FASN P49327 1/20 0.32
CACNA2D1 P54289 1/20 0.31
CACNB2 Q08289 1/20 0.31
CACNA1C Q13936 1/20 0.31
DNM1 Q05193 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5174528 1.00 TSHR (0.46) TSHRALDH1A1FAAHABCG2TRPV1
SCHEMBL2371298 1.00 TSHR (0.46) TSHRALDH1A1FAAHABCG2TRPV1
SCHEMBL15546751 0.83
SCHEMBL9808632 0.80 ALDH1A1 (0.48) TSHRALDH1A1FAAHTRPV1HMGCR
SCHEMBL19974043 0.79 TSHR (0.54) TSHRALDH1A1FAAHABCG2TRPV1
SCHEMBL251339 0.79 TSHR (0.54) TSHRALDH1A1FAAHABCG2TRPV1
SCHEMBL7646309 0.79 TSHR (0.54) TSHRALDH1A1FAAHABCG2TRPV1
SCHEMBL9111564 0.79 TSHR (0.54) TSHRALDH1A1FAAHABCG2TRPV1
SCHEMBL5521453 0.77 FAAH (0.46) TSHRFAAHTRPV1PTGS1PPARG
SCHEMBL20482020 0.77 FAAH (0.46) TSHRFAAHTRPV1PTGS1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9248145-B2 Two alkylresorcinol synthase genes from sorghum; cloning, expression, transformation and characterization THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2016-02-02 US disclosed
WO-2012119152-A1 EXPRESSION OF ISOMERS OF SUCROSE INCREASES SEED WEIGHT, SEED NUMBER AND/OR SEED SIZE TARGETED GROWTH, INC. (US) 2012-09-07 WO disclosed
WO-2011112380-A2 TWO NOVEL ALKYLRESORCINOL SYNTHASE GENES FROM SORGHUM; CLONING, EXPRESSION, TRANSFORMATION AND CHARACTERIZATION THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2011-09-15 WO disclosed
US-20110225676-A1 Two Novel Alkylresorcinol Synthase Genes from Sorghum; Cloning, Expression, Transformation and Characterization THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE 2011-09-15 US disclosed