Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28161105 | 0.88 | AKR1C1 (0.45) | AKR1C1AKR1C3KMT2AADAM17FFAR4 | |
| SCHEMBL15557324 | 0.84 | ADAM17 (0.58) | AKR1C3KMT2AADAM17FFAR4HDAC8 | |
| SCHEMBL349007 | 0.84 | AKR1C1 (0.58) | AKR1C1KMT2APARP10 | |
| SCHEMBL1465003 | 0.83 | KMT2A (0.50) | AKR1C1KMT2AADAM17ALDH1A1 | |
| SCHEMBL23972280 | 0.81 | F2 (0.46) | AKR1C3ADAM17FFAR4PARP10 | |
| SCHEMBL10083334 | 0.80 | MAOB (0.57) | KMT2AADAM17ALDH1A1KDM4E | |
| SCHEMBL21826168 | 0.80 | HDAC3 (0.48) | AKR1C1AKR1C3KMT2AEPHX2 | |
| SCHEMBL11470727 | 0.79 | KMT2A (0.47) | KMT2AADAM17ALDH1A1 | |
| SCHEMBL11479326 | 0.79 | KMT2A (0.47) | KMT2AKDM4EPARP10 | |
| SCHEMBL10083734 | 0.78 | KMT2A (0.46) | AKR1C1AKR1C3KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014015341-A2 | COMPOSITIONS AND METHODS FOR SUBSTRATE-SELECTIVE INHIBITION OF ENDOCANNABINOID OXYGENATION | VANDERBILT UNIVERSITY (US) | 2014-01-23 | — | — | WO | disclosed |