Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13622561 | 0.73 | TDP1 (0.41) | TDP1 | |
| SCHEMBL13183426 | 0.67 | — | — | |
| SCHEMBL8017040 | 0.67 | CYP1A2 (0.38) | TDP1 | |
| SCHEMBL10584170 | 0.64 | — | — | |
| SCHEMBL20210214 | 0.62 | TDP1 (0.50) | TDP1 | |
| SCHEMBL19986440 | 0.62 | TDP1 (0.50) | TDP1 | |
| SCHEMBL20625902 | 0.60 | TSHR (0.33) | TDP1 | |
| SCHEMBL9913299 | 0.60 | — | — | |
| SCHEMBL104635 | 0.60 | — | — | |
| SCHEMBL2737422 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2875016-A1 | CARBAMATE/UREA DERIVATIVES | Novartis AG (CH) | 2015-05-27 | — | — | EP | disclosed |
| WO-2014013469-A1 | CARBAMATE/UREA DERIVATIVES | NOVARTIS AG (CH) | 2014-01-23 | — | — | WO | disclosed |