Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12703373 | 0.86 | TDP1 (0.44) | TDP1CYP1A2CYP2D6APEX1PMP22 | |
| SCHEMBL13995874 | 0.86 | TDP1 (0.44) | TDP1CYP1A2CYP2D6APEX1PMP22 | |
| SCHEMBL13995936 | 0.86 | TDP1 (0.44) | TDP1CYP1A2CYP2D6APEX1PMP22 | |
| SCHEMBL22201501 | 0.85 | TDP1 (0.37) | TDP1CYP1A2CYP2D6APEX1PMP22 | |
| SCHEMBL13540012 | 0.83 | TDP1 (0.35) | TDP1CYP1A2CYP2D6SLC6A4 | |
| SCHEMBL1291692 | 0.81 | TDP1 (0.39) | TDP1CYP1A2CYP2D6APEX1PMP22 | |
| SCHEMBL21909918 | 0.81 | ALDH1A1 (0.45) | TDP1CYP1A2CYP2D6APEX1PMP22 | |
| SCHEMBL18359341 | 0.81 | TDP1 (0.39) | TDP1CYP1A2CYP2D6APEX1PMP22 | |
| SCHEMBL24288643 | 0.78 | TDP1 (0.37) | TDP1CYP1A2CYP2D6APEX1PMP22 | |
| SCHEMBL20210214 | 0.77 | TDP1 (0.50) | TDP1CYP1A2CYP2D6APEX1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11753429-B2 | Cobalt complex, method for manufacturing same, and method for manufacturing cobalt-containing thin film | TOSOH CORPORATION (JP) | 2023-09-12 | — | — | US | disclosed |
| WO-2023093896-A1 | COMPOSITION AND METHOD FOR INHIBITING EXPRESSION OF HEPATITIS B VIRUS (HBV) PROTEIN | 上海舶望制药有限公司 | 2023-06-01 | — | — | WO | disclosed |
| US-20190322643-A1 | HISTONE DEACETYLASE AND HISTONE METHYLTRANSFERASE INHIBITORS AND METHODS OF MAKING AND USE OF THE SAME | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2019-10-24 | — | — | US | disclosed |
| WO-2018050110-A1 | NOVEL CAPSID PROTEIN ASSEMBLY INHIBITOR | 正大天晴药业集团股份有限公司 | 2018-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190322643-A1 | HISTONE DEACETYLASE AND HISTONE METHYLTRANSFERASE INHIBITORS AND METHODS OF MAKING AND USE OF THE SAME | HDAC1, HDAC2, DOT1L | TDP1 1093/4885CYP1A2 3976/4885CYP2D6 4240/4885 |
| US-11753429-B2 | Cobalt complex, method for manufacturing same, and method for manufacturing cobalt-containing thin film | OR10J3, CNOT9, RNF10 | TDP1 4679/4885CYP1A2 342/4885CYP2D6 848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.