Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.58 |
| ▸ | HTR2A | P28223 | 11/20 | 0.52 |
| ▸ | HTR2C | P28335 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1048335 | 0.97 | TAAR1 (0.62) | TAAR1HTR2AHTR2C | |
| SCHEMBL29528231 | 0.97 | TAAR1 (0.62) | TAAR1HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL31069418 | 0.95 | TAAR1 (0.60) | TAAR1HTR2AHTR2C | |
| Ammonia Solution, Strong SCHEMBL27205013 | 0.95 | TAAR1 (0.60) | TAAR1HTR2AHTR2C | |
| SCHEMBL3449783 | 0.89 | TAAR1 (0.54) | TAAR1HTR2AHTR2CALDH1A1CYP2D6 | |
| SCHEMBL28083206 | 0.84 | ALDH1A1 (0.48) | TAAR1ALDH1A1CYP2D6L3MBTL1 | |
| SCHEMBL14965715 | 0.84 | TAAR1 (0.54) | TAAR1HTR2AHTR2CALDH1A1CYP2D6 | |
| SCHEMBL1253319 | 0.82 | TAAR1 (0.77) | TAAR1HTR2AHTR2C | |
| SCHEMBL29364056 | 0.82 | TAAR1 (0.77) | TAAR1HTR2AHTR2C | |
| SCHEMBL2087809 | 0.82 | ALDH1A1 (0.63) | ALDH1A1CYP2D6L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2871955-A1 | HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF | CHDI Foundation, Inc. (US) | 2015-05-20 | — | — | EP | claimed |
| WO-2014014900-A1 | HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF | CHDI FOUNDATION, INC. (US) | 2014-01-23 | — | — | WO | claimed |