SCHEMBL15548355

SCHEMBL15548355

CCCCCOc1cccc(OC(=O)CC)c1OC(=O)CC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
NR1I2 O75469 1/20 0.49
LMNA P02545 1/20 0.49
CHRM2 P08172 1/20 0.49
CYP3A4 P08684 1/20 0.49
ADRA2A P08913 1/20 0.49
MAPT P10636 1/20 0.49
OPRK1 P41145 1/20 0.49
HTR2B P41595 1/20 0.49
SLC6A3 Q01959 1/20 0.49
HDAC6 Q9UBN7 1/20 0.49
PPARG P37231 4/20 0.45
CYSLTR2 Q9NS75 2/20 0.43
CYSLTR1 Q9Y271 2/20 0.43
KDM4E B2RXH2 1/20 0.42
RECQL P46063 1/20 0.42
NAAA Q02083 1/20 0.42
CNR1 P21554 2/20 0.42
CNR2 P34972 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15547875 0.98 LMNA (0.51) MEN1KMT2ANR1I2LMNACHRM2
SCHEMBL15548977 0.98 LMNA (0.51) MEN1KMT2ANR1I2LMNACHRM2
SCHEMBL15548404 0.98 LMNA (0.51) MEN1KMT2ANR1I2LMNACHRM2
SCHEMBL15548164 0.98 LMNA (0.51) MEN1KMT2ANR1I2LMNACHRM2
SCHEMBL15548020 0.98 LMNA (0.51) MEN1KMT2ANR1I2LMNACHRM2
SCHEMBL15548129 0.95 CYP1A2 (0.44) MEN1KMT2ANR1I2LMNACHRM2
SCHEMBL15547824 0.91 NPC1 (0.40) MEN1KMT2ALMNACHRM2MAPT
SCHEMBL15547402 0.90 POLM (0.53) MEN1KMT2ANR1I2LMNACHRM2
SCHEMBL15558846 0.90 MEN1 (0.55) MEN1KMT2ANR1I2LMNACHRM2
SCHEMBL15558509 0.88 POLM (0.55) MEN1KMT2ANR1I2LMNACHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9593172-B2 Ziegler-natta catalyst systems comprising a 1,2-phenylenedioate as internal donor and process for preparing the same INDIAN OIL CORPORATION LIMITED (IN) 2017-03-14 US claimed
US-20150152199-A1 ZIEGLER-NATTA CATALYST SYSTEMS COMPRISING A 1,2-PHENYLENEDIOATE AS INTERNAL DONOR AND PROCESS FOR PREPARING THE SAME INDIAN OIL CORPORATION LIMITED (IN) 2015-06-04 US claimed
EP-2872538-A1 ZIEGLER-NATTA CATALYST SYSTEMS COMPRISING A 1,2-PHENYLENEDIOATE AS INTERNAL DONOR AND PROCESS FOR PREPARING THE SAME Indian Oil Corporation Ltd (IN) 2015-05-20 EP claimed
WO-2014013401-A1 ZIEGLER-NATTA CATALYST SYSTEMS COMPRISING A 1,2-PHENYLENEDIOATE AS INTERNAL DONOR AND PROCESS FOR PREPARING THE SAME INDIAN OIL CORPORATION LIMITED (IN) 2014-01-23 WO claimed
EP-3050906-B1 CATALYST PROCESS MODIFICATION AND POLYMERIZATION THEREOF INDIAN OIL CORP LTD (IN) 2020-07-22 EP disclosed
US-9914789-B2 Ziegler-natta catalyst systems comprising a 1,2-phenylenedioate as internal donor and process for preparing the same INDIAN OIL CORPORATION LIMITED (IN) 2018-03-13 US disclosed
US-9873752-B2 Catalyst process modification and polymerization thereof INDIAN OIL CORPORATION LTD. (IN) 2018-01-23 US disclosed
US-9593172-B2 Ziegler-natta catalyst systems comprising a 1,2-phenylenedioate as internal donor and process for preparing the same INDIAN OIL CORPORATION LIMITED (IN) 2017-03-14 US disclosed
US-20160347880-A1 ZIEGLER-NATTA CATALYST SYSTEMS COMPRISING A 1,2-PHENYLENEDIOATE AS INTERNAL DONOR AND PROCESS FOR PREPARING THE SAME INDIAN OIL CORPORATION LIMITED (IN) 2016-12-01 US disclosed
EP-3050906-A1 CATALYST PROCESS MODIFICATION AND POLYMERIZATION THEREOF Indian Oil Corporation Limited (IN) 2016-08-03 EP disclosed
US-20160215077-A1 CATALYST PROCESS MODIFICATION AND POLYMERIZATION THEREOF INDIAN OIL CORPORATION LTD. (IN) 2016-07-28 US disclosed
US-20150152199-A1 ZIEGLER-NATTA CATALYST SYSTEMS COMPRISING A 1,2-PHENYLENEDIOATE AS INTERNAL DONOR AND PROCESS FOR PREPARING THE SAME INDIAN OIL CORPORATION LIMITED (IN) 2015-06-04 US disclosed
EP-2872538-A1 ZIEGLER-NATTA CATALYST SYSTEMS COMPRISING A 1,2-PHENYLENEDIOATE AS INTERNAL DONOR AND PROCESS FOR PREPARING THE SAME Indian Oil Corporation Ltd (IN) 2015-05-20 EP disclosed
WO-2014013401-A1 ZIEGLER-NATTA CATALYST SYSTEMS COMPRISING A 1,2-PHENYLENEDIOATE AS INTERNAL DONOR AND PROCESS FOR PREPARING THE SAME INDIAN OIL CORPORATION LIMITED (IN) 2014-01-23 WO disclosed