Benzo[1,2,5]Thiadiazole

Benzo[1,2,5]Thiadiazole

SCHEMBL15548644

c1ccc2nsnc2c1.c1scc2c1OCCO2.c1scc2c1OCCO2

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ITGB2 P05107 1/20 0.43
ICAM1 P05362 1/20 0.43
ITGAL P20701 1/20 0.43
SMN1; SMN2 Q16637 5/20 0.39
LMNA P02545 5/20 0.39
CRHBP P24387 2/20 0.39
CRHR2 Q13324 2/20 0.39
HTT P42858 1/20 0.39
NPC1 O15118 5/20 0.38
RAB9A P51151 5/20 0.38
MAPT P10636 4/20 0.38
ALDH1A1 P00352 3/20 0.38
TP53 P04637 3/20 0.38
KDM4E B2RXH2 2/20 0.38
TSHR P16473 2/20 0.38
HPGD P15428 1/20 0.38
CASP1 P29466 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
HSD17B10 Q99714 3/20 0.33
HIF1A Q16665 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4358985 0.76 ITGB2 (0.41) ITGB2ICAM1ITGALSMN1; SMN2LMNA
Benzene SCHEMBL27610541 0.76 ITGB2 (0.48) ITGB2ICAM1ITGALSMN1; SMN2LMNA
SCHEMBL456419 0.76 ITGB2 (0.45) ITGB2ICAM1ITGALSMN1; SMN2LMNA
SCHEMBL33274 0.76
SCHEMBL15982301 0.74 LMNA (0.74) ITGB2ICAM1ITGALSMN1; SMN2LMNA
SCHEMBL15981881 0.74 LMNA (0.74) ITGB2ICAM1ITGALSMN1; SMN2LMNA
SCHEMBL15981864 0.74 LMNA (0.74) ITGB2ICAM1ITGALSMN1; SMN2LMNA
SCHEMBL23247119 0.73 ITGB2 (0.43) ITGB2ICAM1ITGALSMN1; SMN2LMNA
Water SCHEMBL20425715 0.73 ITGB2 (0.43) ITGB2ICAM1ITGALSMN1; SMN2LMNA
SCHEMBL28535767 0.73 ITGB2 (0.43) ITGB2ICAM1ITGALSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2875033-B1 ELECTROCHROMIC COPOLYMERS FROM PRECURSORS, METHOD OF MAKING, AND USE THEREOF THE UNIV OF CONNECTICUT HELTH CENTER (US) 2019-05-01 EP claimed
US-9944757-B2 Electrochromic copolymers from precursors, method of making, and use thereof THE UNIVERSITY OF CONNECTICUT (US) 2018-04-17 US claimed
EP-2875033-B1 ELECTROCHROMIC COPOLYMERS FROM PRECURSORS, METHOD OF MAKING, AND USE THEREOF THE UNIV OF CONNECTICUT HELTH CENTER (US) 2019-05-01 EP disclosed
US-9944757-B2 Electrochromic copolymers from precursors, method of making, and use thereof THE UNIVERSITY OF CONNECTICUT (US) 2018-04-17 US disclosed
US-20150232622-A1 ELECTROCHROMIC COPOLYMERS FROM PRECURSORS, METHOD OF MAKING, AND USE THEREOF UNIV CONNECTICUT (US) 2015-08-20 US disclosed
EP-2875033-A1 ELECTROCHROMIC COPOLYMERS FROM PRECURSORS, METHOD OF MAKING, AND USE THEREOF The University of Connecticut Helth Center (US) 2015-05-27 EP disclosed
WO-2014018472-A1 ELECTROCHROMIC COPOLYMERS FROM PRECURSORS, METHOD OF MAKING, AND USE THEREOF THE UNIVERSITY OF CONNECTICUT (US) 2014-01-30 WO disclosed