SCHEMBL15548704

SCHEMBL15548704

Cc1n[nH]c(C)c1S(=O)(=O)N1CCC(Oc2ccccc2)CC1

nearest known ligand 0.79

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 17/20 0.79
PROKR1 Q8TCW9 17/20 0.79
NAAA Q02083 2/20 0.70
MEN1 O00255 1/20 0.58
CYP2C19 P33261 1/20 0.58
KMT2A Q03164 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15550157 0.91 FPR2 (0.83) FPR2PROKR1NAAA
SCHEMBL15549622 0.89 FPR2 (0.81) FPR2PROKR1NAAA
SCHEMBL15549719 0.88 FPR2 (0.80) FPR2PROKR1NAAA
SCHEMBL15550205 0.88 FPR2 (1.00) FPR2PROKR1
SCHEMBL15537207 0.88 FPR2 (1.00) FPR2PROKR1NAAA
SCHEMBL15548996 0.87 FPR2 (0.77) FPR2PROKR1NAAA
SCHEMBL15547575 0.86 FPR2 (0.80) FPR2PROKR1NAAAMEN1CYP2C19
SCHEMBL15536944 0.85 PROKR1 (1.00) FPR2PROKR1NAAA
SCHEMBL15549087 0.85 FPR2 (0.70) FPR2PROKR1NAAA
SCHEMBL15549545 0.85 FPR2 (1.00) FPR2PROKR1NAAAMEN1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2855449-B1 SULFONYL PIPERIDINE DERIVATIVES AND THEIR USE FOR TREATING PROKINETICIN MEDIATED DISEASES TAKEDA PHARMACEUTICALS CO (JP) 2018-03-07 EP claimed
EP-2855449-A1 SULFONYL PIPERIDINE DERIVATIVES AND THEIR USE FOR TREATING PROKINETICIN MEDIATED DISEASES Takeda Pharmaceutical Company Limited (JP) 2015-04-08 EP claimed
WO-2013179024-A1 SULFONYL PIPERIDINE DERIVATIVES AND THEIR USE FOR TREATING PROKINETICIN MEDIATED DISEASES TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2013-12-05 WO claimed
EP-2855449-A1 SULFONYL PIPERIDINE DERIVATIVES AND THEIR USE FOR TREATING PROKINETICIN MEDIATED DISEASES Takeda Pharmaceutical Company Limited (JP) 2015-04-08 EP disclosed
WO-2013179024-A1 SULFONYL PIPERIDINE DERIVATIVES AND THEIR USE FOR TREATING PROKINETICIN MEDIATED DISEASES TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2013-12-05 WO disclosed