Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.55 |
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | HTR2B | P41595 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4979016 | 0.81 | GPR84 (0.77) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL5851064 | 0.81 | GPR84 (0.77) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL17540815 | 0.81 | GPR84 (0.62) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL8959988 | 0.80 | GPR84 (0.60) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL5822295 | 0.80 | GPR84 (0.79) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL27590147 | 0.79 | GPR84 (0.59) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL27976193 | 0.78 | GPR84 (0.57) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL25291739 | 0.77 | GPR84 (0.60) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL21324414 | 0.77 | GPR84 (0.64) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL17773055 | 0.76 | GPR84 (0.54) | GPR84FFAR1HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013180656-A1 | ICMT Inhibitors | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2013-12-05 | — | — | WO | disclosed |