Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 5/20 | 0.49 |
| ▸ | FPR2 | P25090 | 3/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | CPS1 | P31327 | 8/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.40 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15430492 | 1.00 | FPR1 (0.49) | FPR1FPR2FFAR1CPS1MTNR1A | |
| SCHEMBL14480439 | 0.87 | FFAR1 (0.47) | FPR1FPR2FFAR1CPS1KDM1A | |
| SCHEMBL10289079 | 0.87 | FFAR1 (0.47) | FPR1FPR2FFAR1CPS1KDM1A | |
| SCHEMBL10288350 | 0.87 | FFAR1 (0.47) | FPR1FPR2FFAR1CPS1KDM1A | |
| SCHEMBL2133690 | 0.87 | FFAR1 (0.47) | FPR1FPR2FFAR1CPS1KDM1A | |
| SCHEMBL2133123 | 0.87 | CA1 (0.45) | FPR1FPR2FFAR1CPS1 | |
| SCHEMBL15428484 | 0.84 | FPR1 (0.35) | FPR1FPR2 | |
| SCHEMBL15428485 | 0.84 | CYP1A2 (0.37) | FPR1FPR2 | |
| SCHEMBL15548710 | 0.84 | FPR1 (0.35) | FPR1FPR2 | |
| SCHEMBL1920197 | 0.84 | FPR1 (0.48) | FPR1FPR2CPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2855419-A1 | NEW INDANYLOXYPHENYLCYCLOPROPANECARB OXYLIC ACIDS | Boehringer Ingelheim International GmbH (DE) | 2015-04-08 | — | — | EP | disclosed |
| WO-2013178575-A1 | NEW INDANYLOXYPHENYLCYCLOPROPANECARB OXYLIC ACIDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-12-05 | — | — | WO | disclosed |