Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1555851 | 0.89 | TDP1 (0.41) | KMT2AALOX15CHRNB2CHRNA4LMNA | |
| SCHEMBL5377192 | 0.84 | MAOB (0.40) | KMT2AALOX15TDP1 | |
| SCHEMBL1555841 | 0.77 | APP (0.44) | KMT2AALOX15TDP1 | |
| SCHEMBL1555836 | 0.77 | DRD4 (0.43) | KMT2AALOX15MAPTDRD4TDP1 | |
| SCHEMBL6660834 | 0.76 | TAAR1 (0.52) | KMT2AALOX15CYP19A1TDP1 | |
| SCHEMBL5382684 | 0.75 | KMT2A (0.51) | KMT2AALOX15MAPTCYP19A1GLA | |
| SCHEMBL465983 | 0.74 | TAAR1 (0.54) | KMT2AALOX15TDP1 | |
| SCHEMBL1555319 | 0.73 | SMN1; SMN2 (0.37) | KMT2AMAPTLMNA | |
| SCHEMBL14503517 | 0.72 | KMT2A (0.54) | KMT2AALOX15MAPTCYP19A1LMNA | |
| SCHEMBL5372565 | 0.72 | WDR5 (0.41) | KMT2AALOX15DRD4LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050095-A2 | PREVENTION AND TREATMENT OF POST-OPERATIVE COGNITIVE DYSFUNCTION (POCD) | THE GENERAL HOSPITAL CORPORATION (US) | 2011-04-28 | — | — | WO | disclosed |