Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | PYGL | P06737 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15550335 | 0.89 | BRD4 (0.47) | BRD4MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL15551876 | 0.87 | BRD4 (0.50) | BRD4MAPTENPP2MEN1KMT2A | |
| SCHEMBL15550329 | 0.85 | BRD4 (0.65) | BRD4MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL15551620 | 0.85 | BRD4 (0.50) | BRD4MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL15551540 | 0.84 | BRD4 (0.51) | BRD4MAPTSOS1 | |
| SCHEMBL15550298 | 0.82 | BRD4 (0.46) | BRD4ENPP2ALDH1A1 | |
| SCHEMBL15551621 | 0.81 | HSPB1 (0.54) | BRD4MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL15550839 | 0.81 | BRD4 (0.47) | BRD4MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL15550391 | 0.80 | BRD4 (0.49) | BRD4MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL15552160 | 0.79 | BRD4 (0.50) | BRD4MAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858990-A1 | PYRIDINONE AND PYRIDAZINONE DERIVATIVES | AbbVie Inc. (US) | 2015-04-15 | — | — | EP | disclosed |
| EP-2858982-A1 | PYRIDINONE AND PYRIDAZINONE DERIVATIVES | AbbVie Inc. (US) | 2015-04-15 | — | — | EP | disclosed |
| WO-2013188381-A1 | PYRIDINONE AND PYRIDAZINONE DERIVATIVES | ABBVIE INC. (US) | 2013-12-19 | — | — | WO | disclosed |
| WO-2013185284-A1 | PYRIDINONE AND PYRIDAZINONE DERIVATIVES | ABBOTT LABORATORIES (US) | 2013-12-19 | — | — | WO | disclosed |