SCHEMBL15549372

SCHEMBL15549372

CCCCCC(CCC)C(=O)Oc1ccccc1OC(=O)C(CCC)CCCCC

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 1/20 0.44
PRSS2 P07478 1/20 0.44
PRSS3 P35030 1/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
KDM4E B2RXH2 1/20 0.44
RECQL P46063 1/20 0.44
TSHR P16473 3/20 0.43
CYP3A4 P08684 2/20 0.42
TP53 P04637 1/20 0.42
MAPK1 P28482 1/20 0.42
PTGS2 P35354 5/20 0.42
LMNA P02545 2/20 0.41
ALDH1A1 P00352 2/20 0.41
PPARG P37231 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
NR1I2 O75469 1/20 0.41
CHRM2 P08172 1/20 0.41
ADRA2A P08913 1/20 0.41
MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15549485 0.98 PRSS1 (0.47) PRSS1PRSS2PRSS3MEN1KMT2A
SCHEMBL15548878 0.98 PRSS1 (0.47) PRSS1PRSS2PRSS3MEN1KMT2A
SCHEMBL15548348 0.98 PRSS1 (0.47) PRSS1PRSS2PRSS3MEN1KMT2A
SCHEMBL15548630 0.95 TSHR (0.47) MEN1KMT2AKDM4ERECQLTSHR
SCHEMBL15547906 0.94 PTGS2 (0.51) PRSS1PRSS2PRSS3MEN1KMT2A
SCHEMBL15548420 0.94 MEN1 (0.43) PRSS1PRSS2PRSS3MEN1KMT2A
SCHEMBL15548974 0.93 PTGS2 (0.52) PRSS1PRSS2PRSS3PTGS2PPARG
SCHEMBL15548349 0.93 PRSS1 (0.43) PRSS1PRSS2PRSS3MEN1KMT2A
SCHEMBL15548001 0.93 KDM4E (0.52) PRSS1PRSS2PRSS3MEN1KMT2A
SCHEMBL15547977 0.93 KDM4E (0.56) PRSS1PRSS2PRSS3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9593172-B2 Ziegler-natta catalyst systems comprising a 1,2-phenylenedioate as internal donor and process for preparing the same INDIAN OIL CORPORATION LIMITED (IN) 2017-03-14 US claimed
US-20150152199-A1 ZIEGLER-NATTA CATALYST SYSTEMS COMPRISING A 1,2-PHENYLENEDIOATE AS INTERNAL DONOR AND PROCESS FOR PREPARING THE SAME INDIAN OIL CORPORATION LIMITED (IN) 2015-06-04 US claimed
EP-3050906-B1 CATALYST PROCESS MODIFICATION AND POLYMERIZATION THEREOF INDIAN OIL CORP LTD (IN) 2020-07-22 EP disclosed
US-9914789-B2 Ziegler-natta catalyst systems comprising a 1,2-phenylenedioate as internal donor and process for preparing the same INDIAN OIL CORPORATION LIMITED (IN) 2018-03-13 US disclosed
US-9873752-B2 Catalyst process modification and polymerization thereof INDIAN OIL CORPORATION LTD. (IN) 2018-01-23 US disclosed
US-9593172-B2 Ziegler-natta catalyst systems comprising a 1,2-phenylenedioate as internal donor and process for preparing the same INDIAN OIL CORPORATION LIMITED (IN) 2017-03-14 US disclosed
US-20160347880-A1 ZIEGLER-NATTA CATALYST SYSTEMS COMPRISING A 1,2-PHENYLENEDIOATE AS INTERNAL DONOR AND PROCESS FOR PREPARING THE SAME INDIAN OIL CORPORATION LIMITED (IN) 2016-12-01 US disclosed
EP-3050906-A1 CATALYST PROCESS MODIFICATION AND POLYMERIZATION THEREOF Indian Oil Corporation Limited (IN) 2016-08-03 EP disclosed
US-20160215077-A1 CATALYST PROCESS MODIFICATION AND POLYMERIZATION THEREOF INDIAN OIL CORPORATION LTD. (IN) 2016-07-28 US disclosed
US-20150152199-A1 ZIEGLER-NATTA CATALYST SYSTEMS COMPRISING A 1,2-PHENYLENEDIOATE AS INTERNAL DONOR AND PROCESS FOR PREPARING THE SAME INDIAN OIL CORPORATION LIMITED (IN) 2015-06-04 US disclosed
EP-2872538-A1 ZIEGLER-NATTA CATALYST SYSTEMS COMPRISING A 1,2-PHENYLENEDIOATE AS INTERNAL DONOR AND PROCESS FOR PREPARING THE SAME Indian Oil Corporation Ltd (IN) 2015-05-20 EP disclosed
WO-2014013401-A1 ZIEGLER-NATTA CATALYST SYSTEMS COMPRISING A 1,2-PHENYLENEDIOATE AS INTERNAL DONOR AND PROCESS FOR PREPARING THE SAME INDIAN OIL CORPORATION LIMITED (IN) 2014-01-23 WO disclosed